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pregnancy
Reverse transcription-polymerase chain reaction (RT-PCR) was undertaken to examine the concentration of HGF mRNA and Fas mRNA obtained from 34 cases of HDCP and 30 cases of uncomplicated pregnancy.
      
Morphofunctional State of Epiphysis in Relatively Wild and Domesticated Silver-Black Foxes during Pregnancy
      
Morphological indices of changes in the epiphysis activity during pregnancy are analyzed in relatively wild and domesticated silver-black foxes.
      
The diameter of light actively functioning nuclei of pinealocytes increased most significantly and reliably in the end of pregnancy and, at the same time, the area of their surface decreased.
      
Unlike other stages of ontogenesis, the degree and dynamics of epiphysis activity during the period of pregnancy were similar in animals of both groups.
      
Overall, the studied reproductive hormones could efficiently regulate synthesis of the main Th1 (IFNψ) and Th2 (IL-4) cytokines by T lymphocytes and seem to play the key role in changing the pregnancy-specific pattern of secreted cytokines.
      
On stimulation with mitogens, a high dose of CG (100 IU/ml) significantly increased apoptosis of T-lymphocytes, but its combination with steroid hormones specific for trimester I of pregnancy decreased this parameter.
      
Apoptosis of T-lymphocytes induced by anti-CD95 was suppressed by a high dose of progesterone (100 ng/ml) and also by its combination with CG and estradiol specific for trimester III of pregnancy.
      
The effect of the hormones depended on the cell type and their activation and seemed to be an important mechanism of hormonal control of immune reactions in pregnancy.
      
The hormones were studied separately and in physiological combinations specific for different trimesters of pregnancy.
      
A low dose of CG (10 IU/ml) increased the spontaneous apoptosis of neutrophils, whereas its combination with estradiol and progesterone corresponding to that of trimester III of pregnancy significantly decreased this parameter.
      
Thus, apoptosis of neutrophils is effectively regulated by reproductive hormones; this seems to be an important control mechanism of activation of these cells in pregnancy.
      
Dynamics of Antibody Nuclease Activity in Blood of Women during Pregnancy and Lactation
      
In the present study we have analyzed nuclease activities of antibodies in blood of women during pregnancy and lactation.
      
Although the dynamics of changes in antibody DNase activity during pregnancy was rather individual for each woman, there was a common trend in the increase in antibody activity in the first and/or third trimester of the pregnancy.
      
Extrathymic rearrangement of αβT-lymphocyte antigen receptor genes during pregnancy
      
The existence of αβT-lymphocyte differentiation processes have been demonstrated in mouse peripheral lymphoid organs during pregnancy.
      
The data suggest that during pregnancy the differentiation of αβT lymphocytes may occur not only in central (thymus) but also in peripheral lymphoid organs.
      
A study of the composition of organic compounds in mouse reproductive organs at early pregnancy stages by proton magnetic resona
      
Pregnancy and lactation prevent melanocortin obesity syndrome in mice with Agouti yellow mutation
      
 

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