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The hyperlipidemia model was set up by four-week atherogenic diet, followed by a 16-week treatment in the fenofibrate-treated group (fenofibrate 40 mg/kg every day) and without treatment in the hyperlipidemia group, respectively.
      
In fenofibrate-treated group, the expression of VCAM-1 and leukocyte accumulation on the endothelial surface was decreased, while serum levels of NO were increased as compared with hyperlipidemia group.
      
There was a decrease in both aspartate transaminase and lactate dehydrogenase activities and in malondialdehyde level in liver of the CoPP-treated group compared with controls (p >amp;lt; 0.05).
      
Markedly fewer apoptotic liver cells (determined by TUNEL assay) could be detected in CoPP-treated group compared with the control group.
      
Experimental data on mouse B16 malignant melanoma model indicated that the tumor weight of fusion protein-treated group was statistically significantly smaller than that of interferon γ -treated group.
      
Histopathologic examination revealed that in most healed wounds of Ad-HGF treated group, the dermal layer was thinner, the amount of fibrous tissue was much fewer, and hair follicles growth and sebaceous glands were observed.
      
Both the number of sperm bound to ZP and the rate of fertilized oocytes were significantly reduced in the mannan-treated group compared with the control group.
      
The results indicated a significant increase of SCE frequencies and decrease of MI in the treated group (p >amp;lt; 0.001).
      
Methods: Twelve eight-week-old SHR were randomized into atorvastatin treated group (ATV group,n=6) and distilled water group (DW group,n=6); Wistar-Kyoto rats (WKY) were used as normal controls.
      
Acute rejection occurred in both Group II and the short-term CsA treated group.
      
The A549 cells were divided into four groups: control group, 10-6 mg/ml gemcitabine treated group, 10-4 mg/ml TNP-470 treated group and gemcitabine+TNP-470 treated group.
      
- The social circumstances of the treated group were significantly improved when compared with the controls.
      
The polycythaemic response of IHA-exposed and Trimepranol-treated animals was, therefore, significantly less pronounced as compared with the hypoxic non-treated group.
      
Total cholesterol, phospholipids, and triglycerides in serum were studied during myocardial infarction in a patient group treated with glucose, insulin and potassium (GIK), and a conventionally treated group.
      
There was no difference in the typical changes of cholesterol and phospholipids between the groups, but the GIK-treated group had a late rise in triglycerides.
      
Only the AICAR treated group differed from control.
      
Infarct size amounted to 74±13% in the control group and to 66±19% in the treated group.
      
There was a significant reduction in the size of infarct that developed in the trimetazidine treated group when compared with the controls.
      
In the propranolol treated group there was a slight reduction in infarct size when compared to control, but this was less than in the trimetazidine treated group and did not reach statistical significance.
      
In the adenosine treated group, some decrease of contracture occurred during reperfusion, but values remained significantly higher than in preconditioning.
      
 

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