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bioequivalence
The method was successfully applied to investigate the bioequivalence between two kinds of tablets (test versus reference products) in 18 healthy male Chinese volunteers.
      
Bioanalytical laboratories support a range of regulatory studies ranging from early toxicology studies through Phase 1,2 and 3 clinical studies to definitive bioequivalence and bioavailabity studies in support of the marketed product.
      
With a total run-time of 6 minutes, the method was suitable for supporting clinical studies and applied to the analysis of samples from a bioequivalence study.
      
A new sensitive HPLC-FLD method has been developed and validated for the determination of cisapride in human plasma for a bioequivalence study.
      
This method has been successfully used to support a bioequivalence clinical study.
      
The validated method has been successfully used to analyze human plasma samples for application in pharmacokinetic, bioavailability or bioequivalence studies.
      
The validated method has been applied to analyze the bendroflumethiazide concentrations for application in pharmacokinetic, bioavailability or bioequivalence studies.
      
Determination of Penciclovir in Human Plasma Using LC with Fluorescence Detection: Application to a Bioequivalence Study
      
The assay was successfully applied in a randomized cross-over bioequivalence study of three pharmaceutical products containing 250?mg famciclovir (an oral prodrug of penciclovir) in 18 healthy volunteers.
      
Development and Validation of Atorvastatin by LC-ESI-MS and Application in Bioequivalence Research in Healthy Chinese Volunteers
      
A two-period crossover designed bioequivalence research was also progressed in healthy Chinese volunteers.
      
Simultaneous Determination of Enalapril and Enalaprilat in Human Plasma by LC-MS: Application to a Bioequivalence Study
      
The method was successfully applied for the evaluation of the pharmacokinetics and bioequivalence of enalapril and enalaprilat in 20 healthy volunteers after an oral dose of 20?mg enalapril maleate.
      
The method was simple, specific, precise and accurate and was useful for bioequivalence and pharmacokinetic studies of efavirenz.
      
Quantification of Teprenone in Human Plasma by HPLC Coupled to Mass Spectrometry: Application to a Bioequivalence Study
      
This HPLC-MS procedure was used to assess the bioequivalence of TEP tablet and capsule formulations.
      
The method was successfully applied to the bioequivalence study of pregabalin capsules (150.0?mg) administered as a single oral dose.
      
The method has been successfully applied to the evaluation of pharmacokinetics and bioequivalence of two hydroxyzine hydrochloride formulations in 12 healthy Chinese volunteers after an oral dose of 25?mg.
      
The validated method was successfully used to analyze human plasma samples in bioequivalence studies.
      
The validated method can be applied to pharmacokinetic and bioequivalence studies.
      
 

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