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Overall the pharmacokinetic properties of both isomers were similar in rats, monkeys and humans, with β-isomer exhibiting longer elimination half-life, MRT, volume of distribution and clearance, irrespective of the route of administration.
      
5-FU-PT was given to rats by oral administration at a dosage of 22.5?mg kg-1.
      
In some organs (apart from kidneys, intestinal system, and stomach) the uptake of 99mTc-AA was not significantly affected by the administration of 99mTc with CPR or 99mTc with APAP at 120?min.
      
The administration of 99mTc-AA with PPA in rats caused an increase of the uptake of 99mTc-AA at 120?min in the investigated organs compared to the administration of 99mTc-AA alone.
      
From these data, it may be deduced that the administration of high concentration of 18-methyl norethindrone can displace ketoprofen from its secondary binding site.
      
Specific immune response to this recombinant strain was evaluated by oral administration of the recombinant live bacteria pBO1/S.
      
Alleviation of cell damage in experimental ANP in rats by administration of chondroitin-sulfate reduces
      
Vestibular function was tested at 21:00 on the first day and 1, 3, 5, 7 h after drug administration.
      
Three weeks after drug administration, pAT1a-shRNA1, pAT1a-shRNA2 and valsartan respectively resulted in decrease of the tail blood pressure by (15.1 ± 5.4), (16.4 ± 8.4) and (30.6 ± 18.2) mmHg.
      
Architecture design of Exit-Entry Administration Building of Shanghai Municipal Public Security Bureau
      
combined administration of high-and lowmolecular-weight microbial autoregulators (extracellular RNase fromBacillus intermedius and anabiosis inducing factord1) are reported for the first time for cultured cells of higher eukaryotes.
      
Studies of the effects of combined administration of the autoregulators demonstrated that pretreatment of the cells with low-dosed1 decreased the toxicity of RNase.
      
Changes in trypsin inhibitor activity, lectin activity, and the content of endogenous salicylic acid after administration of exogenous salicylic acid or a pathogen were shown to depend on the resistance of maize strains to Fusarium.
      
Administration of the preparations involving the selected bifidobacteria and lactic acid bacteria assisted in the normalization of the intestinal microflora and activation of protein metabolism in the organism of animals.
      
Experiments on animals showed that native proteins may diffuse into the blood flow after oral administration of diluted protein solutions.
      
The administration of the exogenous NO donor, dinitrosyl iron complexes (DNIC), limited the behavioral disturbances induced by L-DOPA in both rat strains.
      
DSIP and most analogs had no statistically significant effect on sleep compared to the control administration of saline to the same animals.
      
The effects of these two extracts were tested on rats using the open field and passive avoidance tests upon intranasal administration of the extracts (ca.
      
We studied hemocoagulant properties of the amino acid glycinein vitroand after intravenous administration to animals (rats).
      
Intravenous administration of glycine increased the functional activity of the enzymatic fibrinolytic unit of the anticoagulation system.
      
 

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