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diclofenac
Diclofenac (25 mg kg-1) and meloxicam (7.5 mg kg-1) produced 9.3 and 19.6 mm2 ulcer areas in stomachs of rats, respectively, when used alone, but when combined with nimesulide diclofenac and meloxicam did not cause any injury in rat stomachs.
      
While ranitidine at 100 mg kg-1 dose prevented diclofenac-induced ulcer formation, it reduced meloxicam-induced ulcer formation significantly.
      
Determination of diclofenac in pharmaceuticals and urine samples using a membrane sensor based on the ion associate of diclofena
      
The potentiometric response characteristics of a diclofenac selective electrode, based on ion association in different plasticizers, were compared.
      
The potentiometric unit presented a linear response toward diclofenac concentrations between 1 × 10-5 - 5 × 10-2 mol L-1, with slopes of approximately 60 mV dec-1, and exhibited a response time of 3 s.
      
The potentiometric analysis of sodium diclofenac in pharmaceutical formulations was perfomed by the membrane electrode proposed and compared with the results of potentiometric titration given by the Pharmacopoeia of Ukraine.
      
Klinischer Stellenwert von Monointoxikationen mit Ibuprofen, Diclofenac und Metamizol
      
Akutes Koronarsyndrom durch Diclofenac induzierte Koronarspasmen
      
Three days after the acute coronary syndrome the patient developed a podagra, which was treated with colchicinum, diclofenac and local cooling.
      
This case demonstrates that oral application of diclofenac can provoke coronary vasospasm.
      
A liquid chromatographic procedure is described for the determination of acemetacin, diclofenac, indomethacin, ketoprofen, nabumetone, naproxen, piketoprofen, and tolmentin in pharmaceutical preparations.
      
Limits of detection were between 0.01 μ g mL-1 for diclofenac and 0.2 μ g mL-1 for naproxen.
      
Data for samples from thein vivo metabolism of diclofenac was acquired using a novel acquisition mode on a quadrupole-time of flight hybrid mass spectrometer.
      
Real time data-dependent decisions were used to generate product ion spectra for glucuronide and sulfate conjugates of diclofenac eluting from an on-line LC separation.
      
The drugs investigated were the analgesics: Ibuprofen, Fenoprofen, Ketoprofen, Naproxen, and Diclofenac and the decomposition product of acetylsalicylic acid: salicylic acid.
      
Upon additions of different alcohols in the running buffer the change of the binding constant of β-CD with diclofenac sodium was inconspicuous.
      
Two different procedures for simultaneous determination of six NSAIDs (diflunisal, diclofenac, fenoprofen, ibuprofen, naproxen and tolmetin) in environmental waters are described.
      
In this study, two-step isocratic chromatography on silica gel 60F254 HPTLC layer and densitometric quantitation at λ?=?280?nm was developed for the separation of atorvastatin from plasma constituencies and sodium diclofenac as peak-tracer.
      
Simultaneous Determination of Diclofenac Sodium and Rabeprazole Sodium in Bulk and Pharmaceutical Dosage Form by LC
      
A simple, selective, rapid, precise and accurate reverse phase high pressure liquid chromatographic method has been developed for the simultaneous estimation of diclofenac sodium and rabeprazole sodium from pharmaceutical formulations.
      
 

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