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renal-cell
Surgical removal continues to be the mainstay in the treatment of renal-cell carcinoma with neoplastic venous extension.
      
Biochemotherapy of advanced metastatic renal-cell carcinoma: results of the combination of interleukin-2, alpha-interferon, 5-fl
      
Gene therapy on renal-cell carcinoma: magic bullet or tragic insanity
      
Clinically, there is profound skepticism on the use of systemic therapy in renal-cell carcinoma, but since there is no reliable alternative for metastatic disease, innovative approaches including gene therapy seem warranted.
      
Radiolabeled monoclonal antibody G250 in renal-cell carcinoma
      
The current status of iodine 131-radiolabeled monoclonal antibody G250 (mAb G250) in renal-cell carcinoma (RCC) is described.
      
Since renal-cell carcinoma is not significantly radio-or chemosensitive, it is important to investigate new avenues for treatment of this tumor once it has spread, specifically at the molecular level.
      
Whereas both cadherin and catenin dysfunction have been seen in human prostate cancers, only down-regulation of E-cadherin has been shown for bladder cancer and renal-cell carcinoma.
      
Although studies in bladder cancer and renal-cell carcinoma are less mature than studies in prostate cancer, they support the hypothesis that immunostaining for E-cadherin may be of significance for both diagnostic and prognostic purposes.
      
Finally, the E-cadherin-mediated cell-cell adhesion pathway may represent a novel chemotherapeutic target for bladder cancer, prostate cancer, and renal-cell carcinoma.
      
Isolated perfusion of the kidney with tumor necrosis factor for localized renal-cell carcinoma
      
Patients with localized renal-cell carcinoma who are candidates for renal parenchymal sparing surgery are being treated with isolated renal perfusion with recombinant human tumor necrosis factor (TNF).
      
Biology of metastasis and its clinical implications: renal-cell cancer
      
Defects in lymphocytes from renal-cell carcinoma patients with abnormalities in their proliferation, receptor structure, and signal transduction are present.
      
Multiple primary tumors: 17 cases of renal-cell carcinoma associated with primary tumors involving different steroid-hormone tar
      
The aim of this study was to analyze the characteristics of 17 women with renal-cell carcinoma (RCC) associated with other primary neoplasms occurring in steroid-hormone target tissues.
      
Intratumoral interleukin 2 for renal-cell carcinoma by direct gene transfer of a plasmid DNA/DMRIE/DOPE lipid complex
      
Metastatic renal-cell carcinoma (RCC) is not responsive to conventional cytotoxic chemotherapy, but a subset of patients achieve a durable remission with the use of interleukin-2 (IL-2).
      
In preclinical efficacy studies in a murine model of renal-cell carcinoma the direct intratumoral administration of an IL-2 plasmid DNA/DMRIE/DOPE complex resulted in complete tumor regression in the majority of mice.
      
B7-1 gene-modified autologous tumor-cell vaccines for renal-cell carcinoma
      
 

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