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centromere index
A study is presented of the possibilities and limitations of semi-automated karyotype analysis on the basis of chromosome length and centromere index.
      
If there is a correlation between length and centromere index, which is often the case, the axes of the ellipse are tilted.
      
The main reason is that the variation in length and centromere index of a given chromosome in different cells is often much larger than the variation between nonhomologous chromosomes.
      
During metaphase these allocyclic Xs cannot be identified simply by metaphase position or morphology and show a wide range of measurements for arm ratio, centromere index and total length.
      
The centromere index and relative length of human high-resolution G-banded chromosomes
      
The relative length and centromere index were compared in prometaphase and midmetaphase for each human chromosome from five normal men.
      
Chromosome 7 had a significantly different centromere index between prometaphase and midmetaphase, but no difference in relative length.
      
The following three criteria are required for this distinetion: the centromere index, the relative length, and the fluorescence intensity pattern after staining with Quinacrine.
      
On the basis of centromere index and relative chromosome length, four groups of chromosomes could be distinguished.
      
Chromosome C15 turned out to differ in centromere index between varieties.
      
Chromosome length, centromere index, and 15 points from a 64-element density profile were used as features.
      
Length and centromere index by themselves cannot be used to classify chromosomes reliably into their 24 classes.
      
 

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