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idiopathic nephrotic syndrome
Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome
      
Treatment with cyclosporin of patients with idiopathic nephrotic syndrome
      
The prognosis of idiopathic nephrotic syndrome was transformed with the use of corticosteroids and immunosuppressive drugs.
      
Despite these drawbacks, preliminary results showed that approximately two-thirds of patients with idiopathic nephrotic syndrome resistant to other therapy clearly benefited from cyclosporin treatment, whereas only 7% suffered severe side effects.
      
Membranous nephropathy, a disease characterized by an accumulation of immune deposits on the outer aspect of the glomerular basement membrane, is the most common cause of idiopathic nephrotic syndrome in white adults.
      
By contrast, C3PA and C8 showed striking depressions in idiopathic nephrotic syndrome.
      
In a group of 16 children with idiopathic nephrotic syndrome treated with corticosteroids for longer than 12 months, 9 developed a posterior subcapsular cataract (PSC).
      
We investigated lipoprotein profiles in 24 children with normal renal function at different stages of the idiopathic nephrotic syndrome (NS).
      
Impaired zine metabolic status in children affected by idiopathic nephrotic syndrome
      
Therapy of steroid-dependent idiopathic nephrotic syndrome is often unsatisfactory.
      
Long versus standard prednisone therapy for initial treatment of idiopathic nephrotic syndrome in children
      
Two regimens of steroid treatment for the initial attack of idiopathic nephrotic syndrome (NS) in children were compared in a controlled prospective multicentre study.
      
Cerebral sinovenous thrombosis and idiopathic nephrotic syndrome in childhood: report of four new cases and review of the litera
      
The prevalence and pattern of idiopathic nephrotic syndrome, congenital renal anomalies, systemic renal diseases and urinary tract infections are similar to those reported from Europe and the United States.
      
Cyclosporin in the treatment of idiopathic nephrotic syndrome in children
      
Thirty-five children (12 girls, 23 boys), aged from 1 year and 5 months to 14 years at the onset of idiopathic nephrotic syndrome, received cyclosporin A (CyA) because of steroid toxicity or failure to respond to steroids.
      
Two children, one with renal manifestations of systemic lupus erythematosus and the other with idiopathic nephrotic syndrome, were treated with methylprednisolone pulses.
      
There was no difference in GBM thickness between the two groups of nephrotics; the data were subsequently combined and the group referred to as idiopathic nephrotic syndrome.
      
GBM thickness was significantly greater in the idiopathic nephrotic syndrome than in recurrent hematuria (Kruskal-Wallis H test,PO=>amp;lt;0.001).
      
These data also indicate that GBM thickness continues to increase throughout life in patients with idiopathic nephrotic syndrome and recurrent hematuria, perhaps as part of the normal aging process.
      
 

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