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bladder tumor
Using the Timm staining method, the presence of zinc was observed in normal and benign hyperplastic epithelial cells of the rat bladder, particularly in the malignant bladder tumor, induced by the administration of BBN.
      
Our data suggest that: (1) growth and development of the rat bladder tumor, expecially malignant tumors, may have a high requirement for zinc and (2) MT synthesis may be induced by a high zinc concentration in rat bladder tumor cells.
      
This model more closely resembled the characteristics of human bladder tumor when compared to other bladder cancer models.
      
Endoscopic observation for detection and monitoring ofN-butyl-N-(4-hydroxybutyl)nitrosamine - induced bladder tumor in rats
      
When intravesical therapy inN-butyl-N(4-hydroxybu-tyl)nitrosamine (BBN)-induced rat bladder tumor is attempted, it is essential to identify the tumor, to classify its size before therapy and to monitor the effect of the therapy.
      
To establish a more reliable experimental therapeutic system, we assessed the development of BBN-induced rat bladder tumor by endoscopic observation.
      
Cytokine-mediated antitumor effect of OK-432 on urinary bladder tumor cells in vitro
      
Urinary bladder tumor cell lines have different sensitivities to cytokines.
      
It is suggested that in intravesical instillation of OK-432 for treatment of urinary bladder tumor, the optimal dose and interval of instillation should be considered.
      
In vitro investigations of new therapeutic agents on bladder tumor cell lines
      
The prognosis of superficial bladder cancer in terms of recurrence and disease progression is related to bladder tumor multiplicity and the presence of concomitant "plane" tumors such as high-grade dysplasia and carcinoma in situ.
      
Between March 1988 and March 1996 a total of 79 superficial bladder cancer patients were treated with BCG intravesical instillation therapy after transurethral resection of bladder tumor (TUR-Bt).
      
This study was designed to investigate the relationship between expression of matrix metalloproteinase-2 (MMP-2) and invasiveness of human bladder cancer cells, using cell lines derived from a parental human urinary bladder tumor cell line, T24.
      
Inhibition by Vitamin C of DNA adduct formation and arylamine N-acetyltransferase activity in human bladder tumor cells
      
This study reports on the effects of vitamin C on arylamineN-acetyltransferase (NAT) activity and DNA adduct formation in a human bladder tumor cell (T24) line.
      
A total of 45 human bladder tumor patients were analyzed.
      
Using mouse bladder tumor cells (MBT-2 cells), in vitro electrochemotherapy was performed by applying EP to the cell suspension immediately after the addition of anticancer agents.
      
It is clear from in vitro and in vivo studies that, in a murine bladder tumor, the anticancer effect of BLM can be considerably potentiated by applying EP.
      
Further study is needed to determine the exact mechanism of the bladder tumor growth-enhancing effect associated with organ restriction.
      
Extravesical cryosurgical approach for VX2 bladder tumor in rabbits
      
 

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