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thalassemia major
This study explores the psychosocial problems experienced by families with children aged 6 to 14 years suffering from β-thalassemia major (N=188).
      
In order to identify the distribution of gene types of β-thalassemia and reduce the birthrates of β-thalassemia major in Guiyang area, 1054 pregnant women and their spouses from Affiliated Hospital, Guiyang Medical College were screened.
      
Among the 4 cases subject to prenatal gene diagnosis, one fetus was completely normal and 3 fetuses were diagnosed as having β-thalassemia major (1 homozygous and 2 compound heterozygous).
      
The fetuses diagnosed as β-thalassemia major were selectively terminated within two weeks.
      
It was concluded that the birthrate of β-thalassemia major in Guiyang area was reduced and the target of improving birth outcome and child development has been achieved.
      
Urinary zinc excretion and zinc status of patients with Β-thalassemia major
      
In this study, zinc status and urinary zinc excretion with and without desferrioxamine (DFO) infusion and the relationship between urinary zinc excretion and renal tubular dysfunction in thalassemia major (TM) patients were investigated.
      
Serum and fecal pancreatic enzymes in beta-thalassemia major
      
Red blood cell morphology was similar to that of thalassemia major, but they had unusually low levels of HbF (5.0% and 6.8%).
      
ARDS due to Yersinia enterocolitica sepsis in a patient with thalassemia major
      
One of them was due to thalassemia major and the other to thalassemia intermedia.
      
Pituitary gland height evaluated by MR in patients with β-thalassemia major: a marker of pituitary gland function
      
In transfusion-dependent β-thalassemia major, increased iron deposition in the pituitary gland has a cytotoxic effect leading mainly to hypogonadotropic hypogonadism.
      
In 29 patients with β-thalassemia major and 35 age- and gender-matched controls the pituitary gland height was evaluated in a midline sagittal scan using a spin echo T1-weighted (500/20 TR/TE) sequence.
      
A case of beta thalassemia major showing severe maxillary overgrowth and protrusion deformity is presented.
      
MR imaging of deferoxamine-induced bone dysplasia in an 8-year-old female with thalassemia major
      
We present a case of an 8-year-old female with thalassemia major, who had magnetic resonance imaging after plain radiographs had shown metaphyseal changes in the distal femur.
      
Spinal deformities in deferoxamine-treated homozygous beta-thalassemia major patients
      
A new constellation of spinal changes are observed in homozygous beta-thalassemia major (HBT) patients receiving deferoxamine (DF), an iron-chelating drug used in combination with transfusion therapy in certain anemic syndromes.
      
Thirty patients with thalassemia major took part in the study.
      
 

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