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renal interstitial cells
On the enzyme histochemistry of the renal interstitial cells
      
A histochemical study of the renal interstitial cells demonstrates the absence of two of the principal enzymes involved in the citric acid cycle, the cells thus seem to lack the ability to break down fatty acids.
      
On the other hand the renal interstitial cells demonstrate enzyme activity which could be indirect evidence of fatty acid synthesis.
      
Renal interstitial cells play an important role in renal function and renal diseases.
      
We describe the morphology of renal interstitial cells in the healthy kidney.
      
By examining Epon sections of the renal papilla, it is demonstrated that a brief period of salt repletion in salt-depleted rats induces a considerable increase in the number of lipid droplets in the renal interstitial cells.
      
By examining Epon-sections of the renal papilla, it is demonstrated that acute hydration in dehydrated rats induces a considerable increase in the number of lipid droplets in the renal interstitial cells.
      
Probably the isolated lipid material originates mainly from the primary fluorescing lipid droplets of the renal interstitial cells.
      
The findings suggest that the complex lipids of the isolated lipid droplets are synthetized by the renal papilla and probably by the renal interstitial cells.
      
Altogether the results suggest that the lipid droplets of the renal interstitial cells may function as a storage site for prostaglandin precursor.
      
Lysosomal storage of sulfated glycosaminoglycans in renal interstitial cells of rats treated with tilorone
      
PDGF-A mRNA signal of low abundance was detected within renal interstitial cells urothelial cells of the pelvis, and focally within epithelial cells of immature distal convoluted tubules in non-obstructed kidneys.
      
Direct evidence in support of this hypothesis is as follows: vasopressin increases the biosynthesis of PGE2 in renal interstitial cells and in isolated toad bladder.
      
HGF selectively blocks Smad-2/3 nuclear accumulation in renal interstitial cells in obstructive nephropathy.
      
In fetal kidney, positive staining was also evident in some immature renal interstitial cells.
      
Many primitive renal tubules in the neogenic zone of the kidney and many renal interstitial cells expressed moderate levels of E2A.
      
 

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