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The pharmaceutical sciences are advancing rapidly in the post-genomic era of the 21st century with the completion of the human genome, as well as those of many other organisms including bacteria and parasites, and the rapid advances in proteomics.
      
These findings provide compelling evidence that DNA is the ultimate target of these drugs that act on the human genome.
      
Most of the compounds increase the cAMP content of CHO cells expressing the human A1-adenosine receptor, indicating an antagonist activity.
      
Among the nine compounds tested, 5h showed the best selective antiproliferative properties in vitro, being especially active against the human metastatic melanoma cells - inhibition by 93% after 96 h treatment at 10-4 M concentration.
      
1 exhibited significant inhibitory activity against the human DNA topoisomerase I (hTopo I), the cancer cell lines BEL-7402 and MCG-803, with the IC50 values 12.0, 6.5, and 8.0 μg/mL, respectively.
      
All of the above favors the use of software in the magnetic focused conductivity tomography system (MFCT) to reconstruct the image of conductivity within the human body.
      
These ideas were inspired by two aspects: 1) the evolutionary algorithms, the agent, the human-computer cooperation, and the collaborative design theory; 2) the emergency behaviors in ant colonies.
      
Following the ideas, first we constructed the human-computer cooperation agents (hereinafter called the HC-Agents) that combine the human intelligence with evolutionary algorithms.
      
Heavy metal pollutants may enter the human food chain through agricultural products and groundwater from the polluted soils.
      
The human novel gene of ZNF322 is cloned from human fetal cDNA library using the primers on the basis of the ZNF322 sequence analyzed with computer.
      
The presence of this mutation correlated significantly with decreased FHIT expression in the human CRC.
      
Se supplement increase the Se concentrations in the human body.
      
We conclude that the human SART3 DNA vaccine can induce antitumor ability against tumor cells expressing human SART3 (LM8-SART3) in vitro/vivo which may provide new possibilities in antitumor therapy.
      
Meanwhile, the recharge of IMD from outside of the human body is also under investigation.
      
The subject under discussion is a new approach to the problem of structural identification, which relies on the recognition of a decisive role of the human factor in the process of structural identification.
      
The human blood circulation system is represented by a nonlinear oscillation system for computer-aided digital modeling in real time scale.
      
This work deals with the statement and the solution of problems of optimal control of the human immune system affected by a human immunodeficiency virus (HIV).
      
The human cells were isolated from the ventricular brain zone of 9-week-old embryos and cultivated for two weeks before transplantation.
      
Morphofunctional Organization of Lymphoepithelial Organs of the Human Pharynx
      
We present the current concepts of morphofunctional organization of the lymphoepithelial organs in the human pharynx based on the published data and authors" results.
      
 

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