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cytosolic calcium
GD was accompanied by a progressive decrease in the mitochondrial membrane potential and an increase in free cytosolic calcium ions, [Ca2+]i.
      
At the first stage, the cytosolic calcium concentration undergoes temporal and usually local increase due to its entry through the Ca2+ channels.
      
It is supposed that cortical microtubule randomization plays an important role in the changed anisotropy of cell wall extensibility and cytosolic calcium is involved in this process.
      
Cytosolic calcium-dependent phospholipase A2 (cPLA2) has multiple roles including production of arachidonic acid (a key player in cellular signaling pathways) and membrane remodeling.
      
These results enable us to suggest that in hearts of rats presenting spontaneous hypertension, the function of the SR system could account for a normal handling of cytosolic calcium.
      
Calcium uptake of both mitochondria and SR was less sensitive to the action of H2O2 than to HOCl, and the H2O2 effect was less dependent on the cytosolic calcium concentration.
      
A model of cytosolic calcium regulation and autacoids production in vascular endothelial cell
      
A model of vascular endothelial cell is proposed to describe the mechanisms by which cytosolic calcium (Cai) is modulated and endothelium-derived relaxing factor (EDRF) and prostacyclin (PGI2) are released when the cell is stimulated by agonist.
      
We tested the hypothesis that intracellular ANG II exerts effects on cytosolic calcium [Ca++]i in VSMC.
      
The uptake of calcium into the sarcoplasmic reticulum (SR) and its subsequent release from the SR play a key role in the regulation of the cytosolic calcium concentration and the excitation-contraction coupling in cardiac muscle.
      
The changed intracellular calcium homeostasis of the myopathic ventricle favours extrusion of cytosolic calcium by the sodium-calcium exchanger.
      
Laser confocal microscopy determination of intracellular calcium level revealed that exposure to GTP/Cu2+ triggered increase of cytosolic calcium ion, which may be involved in the process of apoptosis.
      
Buffer performance of mitochondria in intracellular calcium signaling is studied in relation to the amount of cytosolic calcium-binding proteins and calcium ion fluxes across the plasma membrane of the cell.
      
The possible effects of zinc on cellular concentrations of CaM, a major cytosolic calcium-binding protein, in the adipocytes derived from obese (ob/ob) mice and their lean counterparts were studied.
      
Collectively, these results suggest that MDMA may be toxic to the heart through its ability to activate the myocardial NF-κB response, disrupt cytosolic calcium and mitochondrial homeostasis, and alter gene transcription.
      
In airway myocytes signal transduction via cytosolic calcium plays an important role.
      
The hypothesis that cytosolic calcium concentration ([Ca2+cyt]) is the primary regulator of parathyroid hormone (PTH) secretion is supported by a number of studies that show an inverse relationship between them.
      
Increased calcium channel expression, β1AR expression, and Na+/Ca2+ exchanger expression together may alter cytosolic calcium.
      
Monitoring cytosolic calcium in parathyroid hormone target cells: Osteoblasts and renal epithelia
      
Receptor occupation at the plasma membrane level results in a production of intracellular messengers, such as cyclic nucleotides (cAMP, cGMP), inositoltrisphosphate (IP3), diacylglycerol (DAG) and a rise in cytosolic calcium concentration.
      
 

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