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time-effect
Time-effect relationship of acupuncture in improving cardiac vegetative nerve function in patients with type II DM
      
By calculating the area under the curve (AUC), of the time-effect curves of the prodrugs, a significantly improved duration of action was found for those prodrugs which have a slow in vitro hydrolysis rate.
      
From time-effect curves the area under the curve for separate time intervals was taken as a measure of dopaminergic activity during that interval.
      
Dose-response and time-effect curves were determined for morphine (1.0-30 mg/kg), levorphanol (0.1 to 3.0 mg/kg), methadone (0.1-3.0 mg/kg), meperidine (1.0-30 mg/kg), oxymorphone (0.03-1.0 mg/kg), and d-amphetamine (0.1-3.0 mg/kg).
      
Dose-response and time-effect curves were also determined for morphine (1.0-30 mg/kg) in rats that had received multiple injections of morphine over a period of 3 days.
      
In a time-effect experiment, the duration of fentanyl's cuing effect was compared with that of its analgesic effect, and it was found that the time-effect characteristics of the narcotic cue are similar to those of analgesia.
      
A preliminary study was conducted to determine the dose- and time-effect curves for midazolam-induced hypothermia.
      
Time-effect determinations revealed that the discriminable properties of ethosuximide were evident as early as 15 min after, and as late as 2 h after, intramuscular injection.
      
Concentration-effect and time-effect relationships of carteolol
      
The concentration-beta blocking effect and time-effect relationships of carteolol were examined in eight normal adults given 15 mg i.v.
      
The latter parameter is considered to be characteristic for the concentration-time-effect relationship.
      
More sound data on dose-time-effect curves in the low incidence range of 10-0.1% tumor incidences could indicated whether the established linearity in the higher incidence range might eventually by interrupted.
      
The pattern of rate variation is consistent with the generation-time-effect hypothesis.
      
In time-effect experiments, after exposure to 0.5 mg L-1 monocrotophos for 1, 2, 4 and 7 days, the activities of two enzymes change in similar trends as found in concentration-effect experiment.
      
Time-effect and dose-effect curves were traced and their relationship with the life span, body weight, erythrocyte and leucocyte count was established.
      
The dose-response and time-effect curves observed following HWI and sodium arsenite treatments were evaluated.
      
Time-effect dummy variables control for unobserved shifts in the data.
      
A time-effect curve measuring the analgesic potency of oral and intramuscular morphine is shown in figure 2.
      
Changes in plasma suPAR from baseline were analysed by Bonferroni-adjusted paired t-test only when the time-effect was significant.
      
If more than 6 strips are used, time-effect may be observed.
      
 

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