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synthesized
Functions of the Laplace operator F(- Δ) can be synthesized from the solution operator to the wave equation.
      
Substituted aryloxypropanolamines (6-20) were synthesized and evaluated for their anorexigenic activity.
      
A library of 363 glycoconjugates and C-nucleosides synthesized by our earlier reported methods were screened for their effect on isolated filarial glutamate cysteine ligase (GCL) and glutathione reductase (GR).
      
Twenty-two nitro- and aminochalcones were synthesized and characterized.
      
Three chemical entities were synthesized as analogs of fenbufen as well as open ring analog of suldinac and celecoxib.
      
Five novel N3S pseudo-peptide chelators derived from mercaptoacetic acid have been synthesized and characterized based on the spectroscopic data.
      
2-Phenethylbenzimidazole, 2-phenethylbenzoxazole and 2-phenethylbenzothiazole derivatives were synthesized to explore the structural features of the serotonin 5-HT2B receptor antagonists.
      
None of the synthesized compounds appear to be more potent than 1 at a concentration of 10 μM.
      
A series of ethers containing pyrrolidine and/or pyridine bioisosteres was synthesized and evaluated as nicotinic ligands.
      
Two series of substituted thiadiazolyl and oxadiazolylquinolines (3a-h, 4a-h, 7a-f, 8a-f and 9) were synthesized and screened for their antimicrobila activity.
      
The synthesized compounds were evaluated as perchlorides and methiodides by functional tests with rabbit vas deferens (putative M1), guinea-pig heart (M2) and guinea-pig ileum (M3).
      
The series of vasicine (1) analogues, an alkaloid from Adhatoda vasica Nees., were synthesized with changes in A, B or C rings.
      
Compounds 3-8 were also synthesized in good yields using microwave-mediated synthesis under solvent free conditions.
      
The synthesized compounds were evaluated as perchlorides and methiodides by functional tests with rabit vas deferens (putatvie M1), guinea-pig heart (M2) and guinea-pig ileum (M3).
      
Novel 5-substituted esters and homologous ester and amido derivatives of 4,5 dihydro-3,3-diethyl-2(3H)-furanone were synthesized and evaluated for anticonvulsant activity in rodents and for affinity to a site on the GABAA receptor complex ([3H]TBOB).
      
A new series of substituted 1-(2-ethylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitriles have been synthesized.
      
A new series of 1,2,3-trisubstituted 2-(2-oxoalkyl)-2,3-dihydrobezimidazoles have been synthesized and evaluated for their cytotoxic activity using one normal (FL) and two cancer (RD and A2058) cell lines.
      
Two of the synthesized compounds proved to be effective in inhibiting HIV-1 replication at micromolar concentrations.
      
The newly synthesized compounds were screened for their antimicrobial activity and were compared with standard drugs.
      
All newly synthesized compounds were evaluated for their antimycobacterial activities against isoniazid-resistant Mycobacterium tuberculosis using agar dilution.
      
 

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