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primary nephrotic syndrome
5-Lipoxygenase and leukotriene A4 hydrolase expression in primary nephrotic syndrome
      
Gene expression of 5-lipoxygenase (5-LO) and leukotriene A4 (LTA4) hydrolase was analyzed in the peripheral blood of 48 children with active primary nephrotic syndrome (PNS) (group I), 27 children with PNS in remission (group II), and 20 controls.
      
The association between HLA class II antigens and childhood primary nephrotic syndrome has been reported in different populations.
      
Most children with primary nephrotic syndrome respond to steroid therapy, but the disease is often characterized by a relapsing course.
      
 

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