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hepatic fibrosis
The Ile50Val polymorphism of the IL4RA gene was tested for association with chronic viral hepatitis and the character of its progression (the stage of hepatic fibrosis).
      
However, a significant difference in genotype frequency distribution was observed for the patients with different stages of hepatic fibrosis.
      
In hepatic fibrosis, the connective tissue biomatrix of the liver changes from the normal matrix, rich in basement membrane collagens, to a matrix enriched in interstitial fibrillar collagens.
      
Viral hepatitis, hepatic fibrosis and hepatocirrhosis etc.
      
Clinical study of Dahuang Zhechong pill in treating posthepatitis B hepatic fibrosis
      
Effect of Danshao Huaxian capsule on the expression of collagen I, III, and caspase-3 in hepatic fibrosis rats
      
Obesity may contribute to hepatic fibrosis directly through induction of inflammatory pathways or indirectly via development of hepatic steatosis and insulin resistance.
      
Hepatic fibrosis: Are any of the serum markers useful
      
The pathogenesis of HCV, which occurs as a consequence of hepatic fibrosis, is much more complex.
      
The hepatic stellate cell, the major producer of the extracellular matrix protein, is the main contributor to hepatic fibrosis, but the mechanism by which HCV induces hepatic fibrosis remains unclear.
      
This proposal was strengthened by an association with hepatic fibrosis.
      
Likewise, the increased prevalence of hemochromatosis gene (HFE) mutations in some studies appears to be largely irrelevant to the development of hepatic fibrosis.
      
Hepatic fibrosis is the scarring response of the liver to chronic liver injury; when fibrosis progresses to cirrhosis, morbid complications can develop.
      
This review describes the ways in which insights into the cellular basis of hepatic fibrosis are leading to realistic strategies for antifibrotic treatment that may revolutionize the management of patients with chronic liver disease.
      
Subsequently, HSCs were found to be key players in the pathogenesis of hepatic fibrosis.
      
Transforming growth factor-βs a profibrotic cytokine that is critical in hepatic fibrosis.
      
Alternative medical strategies to reduce hepatic fibrosis are also under investigation.
      
Classic Caroli's disease involves malformations of the biliary tract alone, whereas Caroli's syndrome refers to the presence of associated congenital hepatic fibrosis.
      
Since its discovery in 1989, HCV has been recognized as a major cause of chronic hepatitis and hepatic fibrosis that progresses in some patients to cirrhosis and hepatocellular carcinoma.
      
If any degree of hepatic fibrosis is present, antiviral therapy for HCV should be considered.
      
 

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