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Finally, we consider the effect on the rate of convergence of not sampling enough local maxima.
      
Finally, we consider the effect on the rate of convergence of not sampling enough local maxima.
      
The method we use is a combination of the smoothing effect of the operator ?t + ?x(2j+1) and a gauge transformation performed on a linear system, which allows us to consider initial data with arbitrary size.
      
Our studies demonstrated an in vivo cardioprotection effect of (N-(3,4,-dimethoxy-2-chlorobenzylideneamino)-guanidine: ME10092) in ischaemic reperfusion injury in the rodent.
      
The compounds were fully characterized by spectral and elemental analyses, and were tested for their effect on gross behavior, antireserpine and anorexigenic activity.
      
No effect was observed on gross behavior and some of them showed fluoxetine like antireserpine and anorexigenic activity.
      
In the present study, the effect of picroliv, an irridoid glycosidic fraction of Picrorhiza kurroa, on the above said parameters of these alcoholic rats was studied.
      
The fibrate class drugs effect on lipid metabolism through PPARα receptor.
      
A library of 363 glycoconjugates and C-nucleosides synthesized by our earlier reported methods were screened for their effect on isolated filarial glutamate cysteine ligase (GCL) and glutathione reductase (GR).
      
The effect of the most promising ones have been looked on the counterparts from mammalian sources and difference in the susceptibility towards enzyme activity inhibition were noted.
      
Among a total of 38 glycosyl ureas, 2 showed more than 50% inhibitory effect.
      
Among a total of 66 glycosyl ureas/ thioureas and glycopeptidyl ureas, 3 showed more than 50% stimulatory effect whereas 2 showed more than 50% inhibitory effect.
      
Among a total of 59 C-nucleosides/ S-containing nucleosides, 24 showed more than 50% stimulatory effect.
      
The 2D QSAR studies revealed that the activity is mainly influenced by electronic parameters where the contribution of field effect and Hammet constant is positive while that of resonance is negaitive.
      
Cytotoxic Effect of Coscinium Fenestratrum (Gaertn.) Colebr.
      
Increased inhibitory effect of methanol extracts over berberine demonstrates the occurrence of other cytotoxic principles along with main active principle berberine or other factors enhancing the cytotoxic effect of berberine.
      
However, no significant inhibitory effect was obtained on superoxide anion formation.
      
Inhibitive Effect of Prodigiosin on the Proliferation of Human Malignant Pancreatic Cancer Cells
      
This inhibitive effect may relate to two factors: mitotic arrest and cell death.
      
The generation of ROS may play an important role in the cytotoxic effect.
      
 

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