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This review presents diverse approaches to cancer biotherapy including bacteriolytic therapy aimed at inducing apoptosis in tumor cells, bacterial vector-based cancer vaccines, and inhibition of tumor neoangiogenesis by microorganisms.
      
Hemopoietic cells but not hepatocytes exhibit significant apoptosis in thiol-free medium and the hemopoietic apoptosis can be inhibited by various thiols, such as L-cysteine, N-acetyl-L-cysteine, and GSH.
      
The contribution of GSH levels in and around fetal liver cells in the triggering of apoptosis in hemopoietic cells is discussed.
      
The present study addresses the contribution of Foscan? (meta-tetra(hydroxyphenyl)chlorine; mTHPC) photosensitized apoptosis in overall cell death in a model of cultured HT29 adenocarcinoma cells.
      
Second, we found that TS induced apoptosis in VSMC associated with increase in O2- generation via NADPH-dependent oxidase.
      
Apoptosis in Unicellular Organisms: Mechanisms and Evolution
      
Data about the programmed death (apoptosis) in unicellular organisms, from bacteria to ciliates, are discussed.
      
In contrast to some animal cells, apoptosis in wheat coleoptile is not accompanied by changes in the set and ratios of H1 histone subfractions.
      
Apoptosis in Wheat Seedlings Grown under Normal Daylight
      
Effect of "External" Superoxide Anion on Apoptosis in Coleoptiles of Wheat Seedlings
      
A derivative of phthalic acid, dibutylphthalate (DBP), which has gametocidal effect at the concentration of ~10-4 M, increased apoptosis in coleoptiles of wheat seedlings.
      
H2O2 intensifies CN--induced apoptosis in pea leaves
      
H2O2 intensifies CN--induced apoptosis in stoma guard cells and to lesser degree in basic epidermal cells in peels of the lower epidermis isolated from pea leaves.
      
By switching on non-cyclic electron transfer in chloroplasts menadione and methyl viologen intensified H2O2 generation in the light, but prevented the CN--induced apoptosis in guard cells.
      
Menadione and methyl viologen did not suppress the CN--induced apoptosis in epidermal cells that, unlike guard cells, contain mitochondria only, but not chloroplasts.
      
Mechanism of estrogen-induced apoptosis in breast cancer cells: Role of the NF-κB signaling pathway
      
Cytoskeleton inhibitors combined with TRAIL induce apoptosis in HeLa carcinoma cells overexpressing antiapoptotic protein Bcl-2
      
TRAIL (Apo2L), a cytokine from the family of tumor necrosis factors (TNF), causes apoptosis in various types of tumor cells but is not toxic for normal cells.
      
Recombinant TRAIL obtained using an original method stimulates the release of cytochrome c from mitochondria into the cytoplasm and apoptosis in HeLa carcinoma cells.
      
Involvement of Apoptosis in the Formation of Vasculogenic Mimicry in the Malignant Neoplasms
      
 

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