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carnosine
Effect of Carnosine on Self-Organization of Mitochondrial Assemblies in Rat Liver Homogenate
      
The effect of carnosine on self-organization of mitochondrial assemblies was studied in rat liver homogenate of quiescent and excited animals.
      
Carnosine was shown to prevent dissociation of assemblies during storage.
      
Prevention of disassembly of organelles by carnosine can serve as one of the mechanisms of carnosine-induced diminishing of muscle fatigue under prolonged work.
      
Carnosine protects erythrocytes from the oxidative stress caused by homocysteic acid
      
Carnosine Modulates Oxygen Consumption and Heat Production by Wheat Root Cells
      
Carnosine protects from the oxidative stress induced by prenatal hypoxia
      
N-trifluoroacetyl-β-alanine in the synthesis of carnosine
      
Their hydrolysis with a solution of sodium hydroxide in aqueous ethanol, followed by acidification with trifluoroacetic acid, led to the formation of β-alanyl-l-histidine (l-carnosine).
      
Some other imidazole-containing compounds (L-histidine,L-histidine methyl ester, andL-carnosine), however, inhibit the Cu2+-catalyzed peroxidation of NADH.
      
Interaction of the vanadyl (IV) cation with carnosine and related ligands
      
The interaction of the vanadyl (IV) (VO2+) cation with carnosine (the dipeptide β-alanyl-histidine) has been investigated by electron absorption spectroscopy at high ligand-to-metal ratios and at different pH values.
      
The results show that in the range 6.0-8.5, the cation interacts with the imidazole group of four different carnosine molecules and points to the presence of an axially coordinated water molecule.
      
These include the basic His containing derivatives: NAH, carnosine, anserine, ophidine, and homocarnosine, and the acidic aspartate derivatives:N-acetyl-l-aspartate (NAA) andN-acetyl-l-aspartylglutamate (NAAG).
      
Differential expression of carnosine, homocarnosine and N-acetyl-L-histidine hydrolytic activities in cultured rat macroglial ce
      
Histidine containing homologs of NAH are β-alanyl-L-histidine or carnosine (Carn) and γ-aminobutyrl-L-histidine or homocarnosine (Hcarn).
      
Carnosine and related compounds protect the double-chain DNA from oxidative damages
      
Carnosine and its derivatives in the concentrations corresponding to their level in excitable tissues have been shown to protect DNA from oxidative damages.
      
Their efficiency (5 mM) was of the following order: ophidine >amp;gt; carnosine ≈ anserine >amp;gt; homocarnosine >amp;gt; N-acetylcarnosine.
      
A semiempirical quantum chemical method PM3 was used to calculate the geometry and energy parameters of the most stable conformations of carnosine and its clusters with water and zinc.
      
 

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