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late-onset alzheimer ' s disease
We have previously demonstrated with MRI that as well as marked white matter involvement in late-onset Alzheimer's disease (AD), atrophy of the corpus callosum may also be present.
      
Variable expression of presenilin 1 is not a major determinant of risk for late-onset Alzheimer's Disease
      
For late-onset Alzheimer's disease (LOAD), numerous studies have reported inconsistent associations with a PSEN1 intronic polymorphism.
      
Complement Factor H Y402H Polymorphism is not Associated with Late-onset Alzheimer's Disease
      
We have genotyped the common complement factor H Y402H polymorphism in a large case-control cohort to investigate association with late-onset Alzheimer's disease susceptibility and find no evidence that this SNP is associated with disease risk.
      
However, it remains possible that another variant in this gene may modify susceptibility for late-onset Alzheimer's disease.
      
Lack of association between the brain-derived neurotrophin factor (C-270T) polymorphism and late-onset Alzheimer's disease (LOAD
      
Genetic association of BACE1 gene polymorphism C786G with late-onset Alzheimer's disease in Chinese
      
The biological functional and genetic association studies indicated that the BACE1 gene might be a genetic risk factor for late-onset Alzheimer's disease (LOAD).
      
Association of MTHFR gene polymorphism C677T with susceptibility to late-onset alzheimer's disease
      
Different studies have attempted to find polymorphisms involved in the serotonergic pathway that could be involved in mood disorders and late-onset Alzheimer's disease (LOAD) symptoms.
      
F2-Isoprostanes as Biomarkers of Late-onset Alzheimer's Disease
      
The biological functional and genetic association studies suggested that the Glu298Asp polymorphism of the ecNOS gene (NOS3) may be a genetic risk factor for late-onset Alzheimer's disease (LOAD).
      
Recent findings suggest that the presence of APOE 4 is associated with an increased risk for both familial Alzheimer's disease and late-onset Alzheimer's disease.
      
Morphological alterations of the choroid plexus in late-onset Alzheimer's disease
      
In our studies apolipoprotein E4 (APOE4) is associated with both early- and late-onset Alzheimer's disease.
      
Association of transferrin C2 allele with late-onset Alzheimer's disease
      
Association between coding variability in the LRP gene and the risk of late-onset Alzheimer's disease
      
The TNFRSF6 variation was further explored in Scottish late-onset Alzheimer's disease (n=159) but no associations were found.
      
The gene encoding IDE is located on chromosome?10 close to a region of linkage for late-onset Alzheimer's disease (LOAD) and thus is a functional and positional candidate for this disorder.
      
 

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