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heart failure
Cardioprotection by Aldosterone Receptor Antagonism in Heart Failure: 1.
      
Thus, the renin-angiotensin-aldosterone system (RAAS) plays a major role in the development of both hypertension and heart failure and is, therefore, a key target for therapeutic interventions.
      
Commonly prescribed medications for control of hypertension and congestive heart failure are inhibitors of the RAAS, including angiotensin converting enzyme inhibitors (ACE-Is) and angiotensin II (A-II) receptor antagonists.
      
These findings support the pivotal role of aldosterone in the pathophysiology of progressive heart failure.
      
Recently, eplerenone was successfully introduced for the treatment of hypertension and heart failure.
      
A growing number of experimental studies are finding a broader role for aldosterone in driving the pathophysiology of both heart failure and hypertension.
      
Twenty-seven CHD patients had coronary insufficiency but not heart failure and had a left ventricle ejection fraction of ≥50%; 26 patients had chronic heart failure and an ejection fraction of >amp;lt;40%.
      
Characteristic features of the electromechanical coupling of the myocardium were studied in patients with heart failure caused by rheumatic heart disease.
      
Association of polymorphic markers I/D of gene ACE and A1166C of gene AT2R1 with ischemic chronic heart failure in the Russian a
      
The density of myocardial and pericardial rat mast cells in isoproterenol-induced heart failure
      
We investigated MC density in the pericardium and myocardium of rats in intact and experimental heart failure (HF) 24 h and 14, 28, and 60 days after two (at 24 h intervals) injections of Isoproterenol (IP) inducing necrosises in the myocardium.
      
Complex clinical-laboratory investigation of children with congestive heart failure developed on the basis of dilated cardiomyopathy and hypertrophic cardiomyopathy has been carried out.
      
Alterations of cardiac and lymphocyte β- adrenoceptors in rat with chronic heart failure
      
The alterations of cardiac and lymphocyte β-adrenoceptors were observed in the rats with chronic heart failure produced by constriction of both abdominal aorta and renal artery.
      
Recruitment of stem cells by hepatocyte growth factor via intracoronary gene transfection in the postinfarction heart failure
      
We aim to study the amelioration effect of adenovirus5-mediated human hepatocyte growth factor gene transfer on postinfarction heart failure in swine model.
      
The amelioration effect of HGF on postinfarction heart failure could not be limited to stimulating angiogenesis, anti-apoptosis, anti-fibrosis, but was also involved in the recruitment of stem cells into myocardium.
      
Structural and functional changes of mitochondria in myocardial cells from heart failure in plateau
      
The majority of the anomalies are of benign prognosis, but others can be associated with cardiac symptoms and syndromes (angina, dyspnea, syncope, congestive heart failure, myocardial infarction and sudden death).
      
Ischemic heart failure enhances endogenous myocardial apelin and APJ receptor expression
      
 

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