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autoimmune disease
The development of lupus-like autoimmune disease of MRL/MpJ-lpr mice is an experimental model for study of autoimmune pathologies and immunopathogenesis.
      
Multiple sclerosis is a chronic inflammatory, putatively autoimmune disease characterized by multifocal demyelination in the central nervous system.
      
Systemic lupus erythematosus (SLE) is an autoimmune disease which occurs in over 80% in women during childbearing years.
      
The association with thymoma and raised AChR antibody suggests that this syndrome represents a unique type of autoimmune disease, in which antibodies against the AChR facilitate rather than inhibit cholinergic action.
      
The occurrence of a chronic inflammatory reaction in one of the two patients supports the idea that an autoimmune disease against GABA-ergic neurons may be involved in SMS.
      
Multiple sclerosis (MS), an autoimmune disease of the central nervous system (CNS) characterized by primary demyelination, is believed to result from an autoimmune attack against myelin components.
      
Gentamicin ototoxicity accounted for a further 17%, while autoimmune disease was present in 9% of patients.
      
There is strong circumstantial evidence that multiple sclerosis (MS) is an autoimmune disease.
      
Patients Eighty-five patients with progressive MS were treated with autologous HSCT in 20 centers and reported to the autoimmune disease working party of the European Group for Blood and Marrow Transplantation (EBMT).
      
Background: Myasthenia gravis (MG) is an autoimmune disease in which impairment of neuromuscular transmission results in a pathological fatigability of striated muscles.
      
Collective evidence supports the notion that multiple sclerosis is principally an autoimmune disease.
      
In addition, glatiramer acetate down-regulates the expression of the Toll-like receptor TLR9, which may be involved in an innate immunity component of autoimmune disease, in a mouse EAE model.
      
Upstream promotion of Treg cell differentiation by blockade of the co-stimulatory molecule CD154 may also be of benefit in preventing autoimmune disease, as illustrated by a promising exploratory Phase I study in multiple sclerosis.
      
Multiple sclerosis is postulated to be a T cell-mediated autoimmune disease characterised by a relapsing-remitting stage followed by a secondary progressive phase.
      
Atherosclerosis - An Autoimmune Disease Due to an Immune Reaction against Heat-Shock Protein 60
      
Multiple sclerosis (MS) is an autoimmune disease characterized by the production of specific types of immunoglobulins into the central nervous system.
      
Catalytic and DNA-Hydrolyzing Activities of Purified Immunoglobulins IgG from Patients Sera with Autoimmune Disease by Pseudobio
      
Another unresolved issue with important neuromuscular implications is whether WNV infection may lead to autoimmune disease.
      
The concept of AE starting with TH2 inflammation, becoming TH1 inflammation in chronicity, and finally progressing to an autoimmune disease with IgE antibodies against autologous epidermal proteins is very attractive.
      
Due to the lack of antibodies, patients usually have recurrent bacterial infections, but there are a number of other puzzling manifestations, including inflammatory conditions, autoimmune disease, and the development of lymphomas.
      
 

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