助手标题
全文文献 工具书 数字 学术定义 翻译助手 学术趋势 更多
查询帮助
意见反馈
共[582]条 当前为第1条到20条[由于搜索限制,当前仅支持显示前5页数据]
 

相关语句
cyclic gmp
Cyclic GMP-Binding Activity in Avena sativa Seedlings
      
Binding of 3H-labeled cyclic GMP (3H-cGMP) to the structural components of subcellular fractions was studied in oat seedlings.
      
Oxygen-mediated pulmonary vasodilation and plasma levels of endothelin-1, atrial natriuretic peptide and cyclic GMP in patients
      
This alteration of the hemodynamic was accompanied by a slight increase of intraparenchymatous concentrations of cyclic GMP (cGMP) while cycle AMP (cAMP) levels were not different from values, measured during normoxia.
      
Experimental data are presented, which suggest that EDRF may act by direct stimulation of guanylate cyclase, resulting in smooth muscle relaxation due to increased smooth muscle cyclic GMP levels.
      
Hemodynamic effects of dibutyryl cyclic GMP in anesthetized dogs
      
Dibutyryl cyclic GMP was given intravenously to anesthetized dogs with doses of 0.0625.
      
Effects of 1 mg/kg dibutyryl cyclic GMP on mean blood pressure and max LV dp/dt were almost equal to those of 3 μg/kg acetylcholine, but dibutyryl cyclic GMP was revealed to have a slower onset and longer acting effects than acetylcholine.
      
The administration of atropine did not block the effect of dibutyryl cyclic GMP but blocked those of acetylcholine.
      
These results indicate that dibutyryl cyclic GMP does not exert these effects through muscarinic receptors in spite of its acetylcholine-like effects.
      
Cyclic GMP inhibits the L-type calcium channel current (ICa), which is the major source of Ca++ entry into heart cells, and which plays a predominant role in the initiation and regulation of cardiac electrical and contractile activities.
      
Nitric oxide (NO) exerts an inhibitory effect on polymorphonuclear neutrophil (PMN) function, via a cyclic GMP-mediated mechanism, while PMNs are known to play an important role in myocardial ischaemia-reperfusion injury (MI-R).
      
During RH the heart generated prostacyclin, nitric oxide, and adenosine as indicated by the appearance of 6-keto-PGF1α, cyclic GMP, urate, inosine, hypoxanthine and xanthine in the perfusate.
      
Negative metabolic effects of cyclic GMP are altered in renal hypertension induced cardiac hypertrophy
      
We tested the hypothesis that increasing myocardial cyclic GMP levels would reduce myocardial O2 consumption and that renal hypertension (One Kidney-One Clip, 1K1C)-induced cardiac hypertrophy would change this relationship.
      
Myocardial cyclic GMP levels were determined by radioimmunoassay.
      
Guanylate cyclase activity was measured by conversion of GTP to cyclic GMP.
      
In control rabbits, cyclic GMP levels (pmoles/g) were higher in SIN-1-treated (EPI: 7.5±1.6; ENDO: 8.1±1.5) than in vehicle-treated animals (EPI: 5.4±0.4; ENDO: 5.6±0.6).
      
This effect was enhanced in 1K1C rabbits, with cyclic GMP levels in the SIN-1-treated group (EPI: 11.9 ±1.3; ENDO: 13.0±1.5) almost double those observed in the vehicletreated group (EPI: 6.3±0.8; ENDO: 7.7±1.1).
      
Thus, there was a greater elevation in cyclic GMP in 1K1C rabbits, but this did not result in a corresponding greater depression in O2 consumption.
      
 

首页上一页12345下一页尾页 

 
CNKI主页设CNKI翻译助手为主页 | 收藏CNKI翻译助手 | 广告服务 | 英文学术搜索
版权图标  2008 CNKI-中国知网
京ICP证040431号 互联网出版许可证 新出网证(京)字008号
北京市公安局海淀分局 备案号:110 1081725
版权图标 2008中国知网(cnki) 中国学术期刊(光盘版)电子杂志社