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metabolite
The pharmacokinetics of α- and β-diastereomers of Arteether, a well-known antimalarial drug and its active metabolite dihydroartemisinin (DHA) were studied in Sprague-Dawley rats, Rhesus monkeys and human volunteers.
      
Biological Evaluation of a Secondary Metabolite, 9-O-methylfusarubin, from Fusarium oxysporum
      
Surprisingly, in the corresponding control set (cultivation of laccase-negative clone without atrazine) an unidentified metabolite having a retention time and UV-spectrum similar to those of atrazine was also found.
      
It has been demonstrated in model experiments that the decrease in the content of BET in the culture fluid is accounted for by the toxin interaction with an attendant product, the exogenous metabolite (EM).
      
Biotransformation of β-carotene with enzyme preparations isolated from the mycelium of Blakeslea trispora resulted in the formation of its hydroxylated metabolite and apocarotenals, products of oxidative degradation of this compound.
      
In all producer strains, the synthesis of these enzymes was induced by arabinose and its metabolite arabitol.
      
Extracellular Protein Metabolite of Luteococcus japonicus subsp.
      
It was shown that the synthesis of this metabolite was dramatically intensified during the stationary growth phase (ten days).
      
Only malate and succinate (but not glutamate) are transported through PBM in mature nodules; and the rate of metabolite translocation through PBM in aging nodules is decreased.
      
Protective effect of extracellular protein metabolite of Luteococcus japonicus subsp.
      
Extracellular protein metabolite isolated from the culture liquid of Luteococcus japonicus subsp.
      
The extracellular metabolite, produced by cells in the logarithmic growth phase, was present in culture liquid in minuscule amounts.
      
More than 80% of the metabolite produced was secreted into the culture medium.
      
The reduced form of the hormone, tetrahydrocortisol, previously considered as an inactive metabolite, when complexed with apolipoprotein A-I, promotes a biological function similar to that of a transcription factor.
      
The findings suggest that the lipoxygenase metabolite of AA, 12-HETE, is a growth-limiting factor for tumor cells of definite type.
      
Until recent years, T2, because of its very low affinity for thyroid hormone receptors (THR), was considered an inactive metabolite of thyroid hormones (TH) (thyroxine (T4) and triiodo-L-thyronine (T3)).
      
The concentration of nitrite, an NO metabolite, was determined using the Griss reaction.
      
When the blood level of the active metabolite of vitamin D3 was set to one-tenth of its norm, the rate of compact bone resorption changed only slightly.
      
The number of components in a low-molecular-weight metabolite fraction (>amp;lt;20 Da) of bacterial strains Bacillus sp.
      
Penicillium citrinum VKM F-1079 was found to produce clavine ergot alkaloids and citrinin, a secondaryO-heterocyclic metabolite.
      
 

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