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The effects of hematopoietic stem/progenitor cells (HSPCs) expanded in the two step coculture with human bone marrow mesenchymal stem cells (hMSCs) on the hematopoietic reconstruction of irradiated NOD/SCID mice were studied.
      
Sublethally-irradiated NOD/SCID mice were transplanted with ex vivo expanded HSPCs with the dose of 8.5 × 106 cells per mouse.
      
SCID-X1 ist eine X-chromosomal vererbte Form der schweren kombinierten Immundefizienz, die durch inaktivierende Mutationen im IL2RG-Gen verursacht wird.
      
After being diagnosed separately by two clinicians using the Turkish version of the Structured Clinical Interview for DSM-III-R (SCID), each subject's free speech was tape-recorded in a standardized session.
      
A structured diagnostic interview (SCID) and an impairment rating (IS) were used as a gold standard to which both questionnaires were compared.
      
The criterion, symptomatology in the early 1990s, was evaluated with the PTSD module of the Structured Clinical Interview for DSM (SCID).
      
Clustering of SCID items in two-dimensional space via multidimensional scaling analysis offers some construct validation for the DSM's differentiation of PTSD symptoms into criterion groups, although there was not a perfect match.
      
Methods: A representative sample categorized 1 year earlier into DSM-III-R psychiatric disorder, subthreshold disorder and no DSM-III-R psychiatric disorder were reassessed with SCID 1 year on.
      
Method: We assessed a representative sample of homeless people (n=102) in the highly industrialised city of Mannheim (Germany) regarding their prevalence of mental disorders (using the SCID) and their needs for mental health care (using the NCA).
      
Enteroviral and Immune Mediated Myocarditis in SCID mice
      
In addition, the two descendant lines (NE11Hp15 and cNE11H) lost their capacity to induce clinical arthritis in SCID mice.
      
Interestingly, two reisolates obtained from the tick midgut reexpressed large amounts of the 22 kDa protein which was recognized by anti-OspC IS and these two reisolates induced clinical arthritis in SCID mice.
      
Establishment of intraperitoneal transplantation model of cisplatin-resistant ovarian carcinoma cell in scid mice
      
Hematopoietic stem cell transplantation (HSCT) has been the definitive therapy for severe combined immune deficiency (SCID) since the first successful transplant for SCID in 1968.
      
Improvements in the use of HSCT to treat patients with SCID are continuing.
      
For example, during the last 5 years, the first successful in-utero HSCT, and the first success with gene therapy have occurred in patients with SCID.
      
Debate still continues about the role of pretransplantation therapy for SCID patients, and the biology of post-HSCT immune reconstitution is under investigation.
      
Severe combined immunodeficiency (SCID) represents a syndrome comprising the most severe forms of inherited immunodeficiencies.
      
The identification of the genetic defects in humans with SCID provides the basis for future therapies for these patients.
      
Ganglioside composition of a mouse brain tumor grown in the severe combined immunodeficiency (SCID) mouse
      
 

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