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breast cancers
The thermostable fraction of serum samples from patients with ovarian, uterus, and breast cancers and benign ovarian tumor was analyzed using two-dimensional electrophoresis combined with MALDI-TOF(-TOF)-mass spectrometry.
      
Familial and inherited breast cancers in Lower Silesia (Poland)
      
The purpose of this study was to determine the frequencies of hereditary and familial breast cancers among Lower Silesian women.
      
The purpose of the study was to determine the epidemiological characteristics of breast cancers diagnosed among Lower Silesian women between 1984 and 2003.
      
The annual number of breast cancers and cancer-related deaths increased markedly between 1984 and 2003.
      
In this review, we provide an overview of these two genes, focusing on their relationship with hereditary breast cancers.
      
BRCA1/2 associated hereditary breast cancers have unique features that differ from the general breast cancers, including alterations in cellular molecules, pathological bases, biological behavior, and a different prevention strategy.
      
But the outcome of BRCA1/2 associated hereditary breast cancers still remains controversial; further studies are needed to elucidate the nature of BRCA1/2 associated hereditary breast cancers.
      
Its incidence is high (more than 50%) in the patients undergoing neurophysiological investigation, and it is considered to be more frequent in subjects with lung and breast cancers.
      
Methods: Protein bax and bcl-2 in 41 breast cancers obtained from operations in our hospital in 1996 were detected using ABC immunohistochemical stain assay and compared with 10 cases with normal breast tissues.
      
Results: Of 32 breast cancers, positive imaging appeared in 25.
      
The frequency of BRCA mutations was identified in familial breast cancers (FBCs) and nonfamilial breast cancers (NFBCs) by molecular genetics, and morphological and immunohistochemical methods.
      
The role of adjuvant chemotherapy in treatment of breast cancers of 1 cm or less is controversial.
      
However, for the majority of patients with breast cancers of 1 cm or less, the minimal benefit of adjuvant chemotherapy does not justify the risk of the treatment.
      
Routine screening mammography has increased the incidence of stage I breast cancers.
      
Preclinical data suggest that BRCA mutation-associated breast cancers may benefit from specific targeted therapeutic approaches.
      
This article is divided into three sections emphasizing the key role of 15-LO-1 in prostate, colorectal, and breast cancers.
      
The expression of FasL mRNA was measured by in situ hybridization in the consecutive tissue slices of 40 breast cancers respectively.
      
The 660-bp sequence was detected in 131 (39%) of 335 unselected breast cancers, in 2 (6.9%) of 29 fibroadenomas, and in 2 (1.65%) of 121 normal breast specimens.
      
Sensitivity and specificity of the model were calculated to obtain the optimal cutoff point for discriminating malignant breast cancers vs other individuals (including benign breast disease and normal ones).
      
 

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