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rat mesangial cells
The transcriptional regulation of SCL was studied in vitro in rat mesangial cells (MC).
      
Effects of cyclosporin a on proliferation of cultured rat mesangial cells
      
CGRP stimulates renin secretion in vivo and in vitro and inhibits contraction of isolated rat mesangial cells by angiotensin II.
      
Calcitonin does not affect vascular resistance, renal blood flow and glomerular filtration, and is less potent in stimulating renin secretion, and does not alter contraction of isolated rat mesangial cells by angiotensin II.
      
Our studies have explored the mechanism of IgG uptake by cultured rat mesangial cells.
      
Transfection efficiency ranged from 5.5% with DMRIE Liposomes in rat mesangial cells to 1.1% with LipofectAmine liposomes in human mesangial cells.
      
Transfection with the human renin expression vector led to the secretion of 11?pg/104 cells/48?h human renin in rat mesangial cells, 3600?pg/104 cells/48?h in 293 cells, and 113?pg/104 cells/48?h human renin in opossum kidney cells.
      
Interleukin 1β did not induce heat shock proteins in rat thyroid cells, rat mesangial cells or in human monocytes.
      
Glucose entry into rat mesangial cells is mediated by both Na+-coupled and facilitative transporters
      
We investigated the relationship between eicosanoid and extracellular matrix production in rat mesangial cells cultured under high glucose vs normal glucose conditions.
      
High glucose level inhibits capacitative Ca2 + influx in cultured rat mesangial cells by a protein kinase C-dependent mechanism
      
Rat mesangial cells were growth-arrested for 24 h with 0.5 % fetal bovine serum in either normal (5.6 mmol/l) or high (30 mmol/l) glucose concentrations or high glucose plus the aldose reductase inhibitor, ARI-509 (100 μmol/l).
      
High glucose-induced intercellular adhesion molecule-1 (ICAM-1) expression through an osmotic effect in rat mesangial cells is
      
There was a significant correlation (r = 0.98, P = 0.0001) between the cyclic AMP data obtained in rat mesangial cells and 5-HT1B binding data reported in rat brain cortex.
      
The same pattern of responses was observed in early passages of primary cultures of rat mesangial cells.
      
This study shows that rat mesangial cells can be used as a convenient source of functional 5-HT1B receptors.
      
To get an insight into intracellular signaling steps, a very early step in the signaling cascade, the biphasic Ca2+ signal elicited by 5-HT and ATP in rat mesangial cells was investigated.
      
Hydrogen peroxide production was measured using a luminol-amplified chemiluminescence assay in three cell types, rat mesangial cells, rabbit proximal tubule cells and Hep-G2 cells, containing different MAO A/MAO B ratios.
      
Inhibition of polyphosphoinositide breakdown and prostaglandin synthesis in rat mesangial cells by islet-activating protein
      
These results indicate that, in rat mesangial cells, angiotensin II induces a homologous desensitization of phospholipase C stimulation.
      
 

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