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regeneration nerve
    Through the independent sample t-test, The recovery degree of regeneration nerve function (the ratio of amplitude of vibration, the ratio of incubation period) and the recovery ratio of fiber with marrow in the two groups were similar (t =0.05, P=0.961; t =0.509,P =0.624;t= -0.22, P=0.832), which indicated the equal functional and ntal morphological recovery of the regenerating nerves.
    经独立样本t检验,两组再生神经功能恢复程度(振幅比、潜伏期比)、有髓纤维恢复率基本相似(t=0.05,P=0.961;t=0.509,P=0.624;t=-0.22,P=0.832),表明两组再生神经有等同的功能和形态恢复程度。
    CONCLUSION: When small gap (2 mm) autogenous vein bridge grafting anastomosis is used to suture the sciatic nerve, the proportion of the proximal end of the sciatic nerve to the original nerve reaches 1/2 or more, the number of regeneration nerve, axonal diameter and myelinated thickness have no conspicuous difference as compared with those of direct anastomosis effect of the entire nerve.
    结论:在应用小间隙(2mm)自体静脉桥接缝合坐骨神经时,近端坐骨神经达到其1/2以上比例时再生神经数、轴突直径和髓鞘厚度与原有神经直接吻合的结果无明显差异。
    Results2 months after operations, the sciatic nerve gap were repaired by the regeneration nerve. There was not evident inflammation in the defects.
    结果术后 2个月再生神经修复了坐骨神经的缺损 ,实验动物未出现排斥反应及明显的炎症反应。
    ②Gross observation: After 12 week of operation, there was much regeneration nerve fiber in myoblast group and extracellular matrix gel group, like normal nerve; The diameter was thinner than normal nerve trunk. It was slightly thicker in the myoblast group than that in the extracellular matrix gel group.
    ②大体观察:术后12周,成肌细胞组和细胞外基质凝胶组均可见再生神经,外形似正常神经,直径较正常的神经干细,成肌细胞组略粗于细胞外基质凝胶组。
    There was no regeneration nerve through gap in saline group.
    生理盐水组导管内无再生神经通过间隙。
    In vivo ,the number of nerve regeneration,nerve fibers arrangement,myelination and nerve function reconstruction in NGF/PLGA nerve guide conduits were better than those in PLGA nerve guide conduits.
    NGF/PLGA神经导管组在促进坐骨神经再生、再生神经纤维排列规律化、提高再生神经髓鞘化、加速再生神经功能重建等方面均优于单纯PLGA导管组,比自体神经移植组略差。
 

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