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    The cell apoptosis rate of control was higher than that of 0.8 and 7.5 mg·kg -1 TP groups(P<0.01).
    流式细胞术结果中 ,对照组细胞凋亡率高于 0 .8及 7.5mg·kg-1TP组(P <0 .0 1 )。
    Results Compared with the sense group which were transfected by sense oligonucleotide of clusterin,the antisense group which were transfected by antisense oligonucleotide of clusterin exprerienced increase in apoptosis of EJ cells,reaching the peak on day 5 with apoptosis rate of 80%. The difference between the 2 groups was statistically significant ( P <0.05).
    结果 转染clusterin反义寡核苷酸组 (反义组 )EJ细胞凋亡增加 ,第 5天达峰 ,凋亡率 80 % ,与转染clusterin正义寡核苷酸组 (正义组 )比较 ,差异有显著性意义 (P <0 .0 5 )。
    Partial cancer cells presented the characteristic morphological changes of apoptosis with the apoptosis rates being 18.0 % to 20.6 % (P<0.01).
    部分癌细胞呈现凋亡形态学变化 ,凋亡率为 18.0 %~ 2 0 .6 % (P <0 .0 1) ;
    Objective To study the apoptosis (AP)and androgen receptor (AR) isoforms as well as androgen estrogen level in normal prostatic ductal system and hyperplastic tissues.
    目的研究前列腺导管系统远、近端组织的细胞凋亡率、雄激素受体(AR)亚型表达及其雄、雌激素环境,以探讨诸因素在前列腺增长和前列腺增生(BPH)发病中的作用。
    Results The rates of apoptosis of bladder cancer cell T24、5637 were 20.1%、47.5% by treated with 100 μg/l TRAIL singly,which had significant difference compared with the groups without agents(P<0.01);
    结果  10 0 μg/LTRAIL引起T2 4、5 63 7细胞的凋亡率分别为 2 0 .1%、45 .3 % ,与无药物组 1.1%、3 .5 %的凋亡率比较差异有非常显著性(P <0 .0 1)。
    Renal function was positively related to the lymphocyte apoptosis rate ( P < 0. 01).
    肾功能指标与淋巴细胞凋亡率呈正相关(P<0.01)。
    Results The IC 50 value of gossypol acetate for T 24 cells was found to be 126.3 μmol·L -1. The apoptotic cells were induced by gossypol acetate at the concentration of 50~300 μmol·L -1.Conclusion Gossypol acetate can inhibit human T 24 urinary bladder cancer cells and induce apoptosis at some concentrations.
    结果 MTT法测得其IC50 值为 12 6.3 μmol·L-1,浓度为 5 0~ 3 0 0 μmol·L-1的棉酚具有诱导T2 4 细胞凋亡的作用 ,随着药物作用时间的延长凋亡率增加。
    Conclusion The therapeutic effects of high dose of estrogen might be related with the inhibitory expression of Bcl-2,and promoting expression of Bax in TZ.
    结论 大剂量雌激素对BPH治疗作用可能与其抑制TZ细胞Bcl 2的表达和促进Bax的表达进而提高细胞凋亡率有关。
    Objective To assess the clinical significance of the expression of ki 67,bcl 2,bax,p53 protein and the spontaneous apoptosis in human renal clear cell carcinoma.
    目的 探讨人肾透明细胞癌中 ki- 6 7、bcl- 2、bax、p5 3表达及癌细胞自发凋亡率的临床意义。
    The tumor spontaneous apoptosis index (AI) was 0.2%~15.4% which had the increasing trend with the rising of TNM stage.
    癌细胞自发凋亡率 ( AI)为 0 .2 %~ 15 .4 % ,随 TNM分期的增高有上升趋势。
    Methods Bladder cancer T24cells were treated with Celecoxib at the various doses in incubation media and also co-treated with mitomycin(MMC). The cell growth inhibition rates were measured by MTT assay and apoptotic rate was detected with flow cytometry(FCM).
    方法用MMT比色法、AnnexinⅤ流式细胞分析术(FCM)分别观察不同浓度Celecoxib及其联合丝裂霉素C(MMC)作用不同时间后膀胱肿瘤T24细胞系的生长抑制率及凋亡率
    The apoptotic rate was (69.40±0.80)% (P<0.05).
    凋亡率为 (69.40± 0 .80 ) % (P <0 .0 5 )。
    Flow cytometry was used to determine the effects of cellular growth inhibition. Results The apoptosis rate induced by 5 μmol/L 4-HPR and 0.05 mg/L adriamycin was 8% and 21% respectively on T24 cells and apoptosis reached 52% (P<0.05) after combined use of these two agents.
    结果 单用 5 μmol/L的 4 HPR、0 .0 5mg/L阿霉素诱导T2 4细胞凋亡率分别为 8%和 2 1% ,两药联合后凋亡率达 5 2 % (P <0 .0 5 )。
    Apoptosis rate induced by 0.5 mg/L adriamycin was 52% and then raised to 81% and 95% respectively (P<0.05) after acted together with 1 μmol/L and 5 μmol/L 4-HPR. The combination of 4-HPR and ADM had a synergistic effects on apoptosis induction in T24 cell line.
    0 .5mg/L阿霉素对T2 4细胞凋亡率为 5 2 % ,联合1、5 μmol/L的 4 HPR后凋亡率上升至 81%和 94% (P <0 .0 5 )。
    Apoptotic rates of tumor cells attached to FN were 1.4%, 1.0% at 2 hours, 12 hours after exposed to MMC, while those of cells attached to BSA were 4.9%, 8.2% respectively. Apoptotic rates had significant difference between FN and BSA group (P< 0.01).
    FN黏附的膀胱肿瘤细胞在不同浓度MMC作用 2h和 12h后平均凋亡率分别为 1.4 %和 1.0 % ,而BSA组的细胞平均凋亡率为4 .9%和 8.2 % ,两组比较差异有统计学意义 (P <0 .0 1)。
    After BIU87 and T24 were treated with means of the IC 50 of two cell lines ,after 72 hours,the apoptosis of emodin treated cell lines showed 44.5% and 77.3% respectively(P<0.01). The adriamycin showed 56.9% and 57.3% respectively,(P>0.05).
    两细胞株的平均IC50 浓度作用于BIU87和T2 4 ,大黄素细胞凋亡率分别为 4 4 5 %和 77 3% (P <0 0 1) ,阿霉素分别为 5 6 9%和 5 7 3% ,P >0 0 5。
    Hypodiploid peaks on FCM histogram. Apoptosis rate were 6.8%、25.1%、28.6%、36.6%、41.1% and 21.4%、27.2%、28.5%、36.8%、47.7%;
    流式细胞仪直方图上见亚二倍体峰 ,2株癌细胞均出现凋亡 ,凋亡率分别为 6.8%、2 5 .1%、2 8.6%、3 6.6%、41.1%和 2 1.4%、2 7.2 %、2 8.5 %、3 6.8%、47.7% ;
    Apoptosis rate were 6.8%、25.1%、28.6% 、36.6%、41.1% and 21.4%、27.2%、28.5%、36.8%、47.7%; Moreover,the cell cycle could be arrested at G1/S checkpoint,also make G1 phase cell markedly increasing and the cell proliferating index (Pl) also decreasing.
    流式细胞仪直方图上可见亚二倍体峰 ,癌细胞出现凋亡 ,凋亡率分别为 6 8%、2 5 1%、2 8 6 %、36 6 %、4 1 1%和 2 1 4、2 7 2 %、2 8 5 %、36 8%、4 7 7% ;
    The NO concentration was (76.7± 10.4) μmol/L and the apoptosis rate of spermatogenic cells was (3.8±1.3)% in 15 normal fertile men, while those of the 15 infertile cases were (112.7±14.3) μmol/L and (4.7± 1.9)% respectively.
    15例正常生育组精浆NO含量为 (76 .7± 10 .4 ) μmol/L ,生精细胞凋亡率为 (3.8±1.3) % ; 15例不育组NO含量为 (112 .7± 14 .3) μmol/L ,生精细胞凋亡率为 (4 .7± 1.9) % ;
    The apoptosis rate of spermatogenic cells was (16.3±4.0)% in 12 male infertile cases with NO level over 135 μmol/L.
    12例不育组精浆NO含量高(>135 μmol/L)者的生精细胞凋亡率为 (16 .3± 4 .0 ) % .
 

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