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surgery alone
    Methods 38 patients with stage Ⅲ A NSCLC were randomly and equally allocated into neoadjuvant chemotherapy group and surgery alone group.
    方法  3 8例ⅢA 期NSCLC患者随机分为新辅助化疗组 (19例 )和单独手术组 (19例 )。
    Surgery resection rate was 94.7%,and complete resection rate was 57.9% in neoadjuvant chemotherapy group,which were much higher than those in surgery alone group(78.9% and 36.8% respectively).
    新辅助化疗组的手术切除率 94.7% ,手术完全性切除率 5 7.9% ,明显高于单独手术组患者 (P <0 .0 5 ) ,其手术切除率和完全性切除率分别为 78.9%和 3 6.8%。
    Perioperative Chemotherapy versus Surgery alone for Resectable Gastroesophageal Cancer.
    手术期间化学疗法与单独手术治疗可切除的胃食管癌疗效比较
    Surgery alone group were treated by operation only.
    单独手术组患者确诊后直接手术治疗。
    Methods:Expression of p53,c-erbB-2and VEGF in18patients with NSCLC who received radi -cal surgery and cisplatin -based chemotherapy were d etermined by LSAB immunohistochemical method in contrast with15NSCLC patients received surgery alone.
    方法:应用免疫组化LSAB方法检测18例根治术后行含铂类辅助化疗的Ⅲa期非小细胞肺癌石蜡切片中p53、c-erbB-2、VEGF蛋白的表达情况,选同期单独手术的15例Ⅲa期患者作对照,分析三项指标在单纯手术组和术后化疗组中的表达以及联合检测三项指标对预后和辅助化疗的预测作用。
    Methods Expression of VEGF and c-erBb-2 in 35 patients with NSCLC who received radical surgery and cisplain-based chemotherapy were determined by LSAB immunohistochemical method in contrast with 21 NSCLC patients received surgery alone. Kaplan-Meier method was used to analyze the correlation of their expression with prognosis and predictive value in chemotherapy.
    方法应用免疫组化LSAB法检测35例根治术后行含铂类辅助化疗的Ⅲa期非小细胞肺癌VEGF、c-erbB-2蛋白的表达情况,选同期单独手术的21例Ⅲa期患者作对照,分析两项指标在单纯手术组和术后化疗组中的表达以及联合检测两项指标对预后和辅助化疗的预测作用。
    Methods Expression of p53 in 18 patients with NSCLC who received radical surgery and cisplatin-based chemotherapy after operation and 20 patients received radiotherapy after radical operation were determined by LSAB immunohistochemical method in contrast with 15 patients with NSCLC received surgery alone. Kaplan-Meier method and Cox proportional hazard model were used to analyze.
    方法应用免疫组化LSAB方法检测NSCLC石蜡切片中p53蛋白的表达情况,选取18例根治术后行含铂类辅助化疗和20例根治术后行辅助放疗的Ⅲa期NSCLC,选同期单独手术的15例Ⅲa期患者作对照,应用Kaplan-Meier法和多变量Cox比例风险模型进行分析。
    Methods Expression of C-erbB-2 protein in 18 patients with NSCLC who received radical surgery and cisplatin-based chemotherapy after operation were detected (surgery plus chemotherapy group )by LSAB immunohistochemical method in contrast with 15 patients with NSCLC received surgery alone (single surgery group). Kaplan-Meier method and Cox proportional hazard model were used to analyze.
    方法应用免疫组织化学LSAB方法检测18例根治术后行含铂类辅助化疗的Ⅲa期非小细胞肺癌(术后化疗组)石蜡切片中C-erbB-2蛋白的表达情况,选同期单独手术的15例Ⅲa期患者(单纯手术组)作为对照,应用Kaplan-Meier法和多变量Cox比例风险模型进行分析。
 

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