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proliferating cells
    Studies on Mechanism of Indirubin Action in Treatment of Chronic Granulocytic Leukemia Ⅱ.Effects of Indirubin on Nucleic Acid and Protein Synthesis in Animal Transplantable Tumor Cells and Normal Proliferating Cells in Vitro
    靛玉红治疗慢性粒细胞白血病疗效原理的研究Ⅱ.靛玉红在体外对动物肿瘤细胞和正常增殖细胞核酸与蛋白质合成代谢的影响
    The proliferating cells in the rat endolymphatic sac
    大鼠内淋巴囊的增殖细胞
    Topo Ⅱα gene is located in chromosome 17q21-22 region. The molecular weight of Topo Ⅱα is 170kD. Topo Ⅱα is expressed in proliferating cells and mainly located in the nuclear ground substance.
    TopoⅡα基因定位于染色体17q21-22,其蛋白分子量为170kD,存在于增殖细胞,主要分布于核基质中。
    The results showed:1.PJV had no direct cytotoxicity on the YAC-1 tumor cells,but it could stimulate the mononuclear spleen cells to proliferate in the concentration of 3.9 to 62.5% μg/ml,and the proliferating cells had no killer activity on the tumor target cells.
    结果表明:1.PJV对YAC-1肿瘤靶细胞在3.9~62.5μg/ml浓度范围内对单个核脾细胞有明显的刺激增殖作用,此增殖细胞对肿瘤靶细胞无杀伤作用; 2.PJV在LAK细胞的诱导阶段可增加其诱导数量和增殖活性,提高杀伤活性,但PJV在LAK细胞杀伤阶段对其活性无影响;
    The ratio of apoptotic to proliferating cells in hyperplasia and dysplasia was 1∶1.3~1.4, 1∶1.1~1.2 respectively, and 1∶ 2.3~ 2.4 in breast cancer.
    在乳腺单纯性增生和不典型增生中,凋亡细胞和增殖细胞密度比例分别为1∶1-3 至1∶1-4 ,1∶1-1 至1∶1-2 ; 而在乳腺癌中其密度比例约为1∶2-3 至1∶2-4 。
    Results The number of apoptotic cells decreased gradually along with the increase of malignancy of NHL. On the contrary,the number of proliferating cells was much higher in the moderate and high malignancy group than that in the low malignancy group( P <0.01).
    结果随着NHL恶性程度的增高,凋亡细胞数量逐渐减少,与此相反,中度恶性组及高度恶性组的增殖细胞数量明显高于低度恶性组(P<0.01)。
    the proliferating cells was 2.862 × 103/ml, 8.725 × 103/ml, 12.249 × 103/ml, 18.823 × 103/ml respectively.
    增殖细胞密度分别为2.862×10~3/ml、8.725×10~3/ml、12.249×10~3/ml、18.823×10~3/ml。 伤后7d内无明显的牵引性机网膜脱离(TRD)出现,在第35d,TRD的发生率为81.3%(26/32)。
    Results 1.The expressions of Pax-6 were mainly localized in NSCs and hippocampus proliferating cells of developing rat brains;
    结果  1 在发育中大鼠脑内 ,Pax 6主要表达于神经干细胞内 ,在海马增殖细胞亦有较高表达。
    The number of the inflammatory cells and the proliferating cells weregreater in Group C than in Groups A and B. There was a statistically significant difference (P<0. 05), At 20 and 30days after operation, the content of hydroxyproline was greater in Group C than in Group A and B. There was astatistically significant difference (P<0. 05).
    C组术后各时间点炎性细胞计数、皮下组织及肉芽组织内增殖细胞数明显高于A、B组,术后20、30 d,羟脯氨酸含量高于A、B组,差异有统计学意义(P<0.05); 3组内皮细胞计数,差异无统计学意义(P>0.05)。
    However,there was no statistically significant difference between Group Aand Group B in the wound healing rate, the numbers of the inflammatory cells, vascular endothelial cells and proliferating cells, and the content of-hydroxyproline (P>0. 05).
    A、B组创面局部情况、创面愈合率、病理组织学检查、炎性细胞数计数、血管内皮细胞计数、增殖细胞计数和羟脯氨酸含量,差异均无统计学意义(P>0.05)。
    During this excessive processof wound healing, the retinal pigment epithelium (RPE) is one of themost importantly proliferating cells This study consists of two parts:To observe the proliferative state of migrated RPE in specimenobtained from vitrectomy in ocular injured patients and that of RPE insitu in experimental RD model.
    在这一过程中,色素上皮细胞(RPE)是主要的增殖细胞之一。 本实验分别观察外伤眼经玻璃体切割手术获取的增殖组织内迁移 RPE和实验性 RD动物模型原位 RPE细胞的增殖活性。
    Cells were challenged with FSH (0.25-1.0 ID/ml) or E2 (10"8~10"5M) alone and in combination. The number of germ cells was counted and the proliferating cells were immunolocalized by a specific antibody againstproliferating cell nuclear antigen (PCNA). PCNA-LI (labeling index, percentage of PCNA-positive germ cells to the total germ cells) was determined for germ cells.
    首先验证该培养模型对激素的反应性,用卵泡刺激素(FSH) (0.25~1.0IU/ml)和17β-雌二醇(E_2)(10~(-8)~10~(-5)M)单独或联合处理细胞,培养48h后,观察细胞数目变化并用PCNA免疫细胞化学显示增殖细胞,计算生殖细胞的PCNA标记率(LI)。
    The proliferating cell neclear antigen ( PCNA) gathers more coenzyme for DNA. PCNA can lie in normal proliferating cells and cancer cells. It can present the character of cell proliferation.
    增殖细胞核抗原(PCNA)是DNA聚合酶的辅助蛋白,可存在于正常的可增殖细胞及肿瘤细胞,是反映细胞增殖活性的良好指标。
    MCM proteins express in high level in proliferating cells, and in low level or never in GO phase cells or differentiated cells, so MCM proteins may be a special marker of proliferating cells.
    MCM蛋白在增殖细胞中表达水平高,在静止期细胞或分化好的细胞中不表达或水平很低,提示MCM蛋白可以作为增殖细胞的特异标志。
    The effects of indirubin on nucleic acid and protein synthesis in animal transplantable tumor cells and normal proliferating cells have been studied in vitro.
    本文研究了靛玉红对动物可移植性肿瘤细胞和正常增殖细胞核酸和蛋白质合成代谢的影响。
    3HTdR-autoradiography and Feulgen reaction were carried out successively in smear preparations of single cells. The proportion of proliferating cells ( S, G2 ) labeled by silver grains was counted, then Feulgen-density of unlabeled cells (G1 ) in the same slide was determined cytophotometrically.
    将单个细胞涂片连续进行~3HTdR-放射自显术和福尔根反应,先计算银粒标记的增殖细胞(S,G_2)的比例,再用细胞光度法测量未标记细胞(GI)的福尔根光密度。
    Strong nucleolar fluorescence is observed in human cancer cells and proliferating cells but not in normal human lymphocytes and non-proliferating tissues.
    其在静止的人淋巴细胞和人正常非增殖组织中基本不表达或仅有微量表达,在人癌细胞和人正常增殖细胞中表达.
    The distribution of proliferating cells, corresponds to the area where the microvascular density is high, mainly in the periphery and basal parts of cancer nests.
    研究结果表明,微血管密度改变和增殖细胞比例变化均反映了肿瘤组织的恶性特征。 增殖细胞分布区域与颊癌内微血管密集增生区域相一致,主要分布在肿瘤周边部和癌巢的基底部;
    The density of apoptotic cells in HCC was significantly lower than that in cirrhosis, and the density of proliferating cells was much higher in HCC than that in cirrhosis.
    结果显示:HCC中凋亡细胞密度显著低于肝硬变,而增殖细胞密度明显高于肝硬变。
    On day 21,MMP 2 expression returned to basic level. Cell cycle analysis suggested that the number of proliferating and apoptotic cells increased remarkably during vascular restenosis development. With the extension of the time of endothelial injury,both the proliferating cells and apoptotic cells increased,but the proportion of the former was higher than that of the latter.
    第21 d,MMP-2表达恢复正常,胶原合成和降解仍维持在较高水平.流式细胞分析结果显示,血管内皮剥脱后进入增殖状态及发生凋亡的细胞显著增加,增殖细胞所占比例高于凋亡细胞,且两者均随内皮损伤后的时间延长而增加.
 

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