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    Effect of Estrogen on Ultramicrostructure of Rats Pancreatic Precancerous Lesion Induced by Azaserine
    雌激素对大鼠胰腺癌前病变超微结构的影响
    THE EXPERIMENTAL STUDY OF ESTROGEN EFFECT ON PRECANCEROUS LESION AND K-ras MUTATION IN RATS ' PANCREATIC ACINAR CELLULAR CANCER
    雌激素对大鼠胰腺癌前病变及K-ras基因突变影响的实验研究
    THE EXPERIMENTAL STUDY OF ESTROGENS EFFECT ON DNA CONTENT IN PRECANCEROUS LESION OF RATS PANCREATIC CANCER INDUCED BY AZASERINE
    雌激素对Azaserine诱导大鼠胰腺癌癌前病变DNA含量影响的实验研究
    Development of a new rat model of pancreatic cancer
    一种新型大鼠胰腺癌模型的制备
    Inhibition of angiogenesis inhibitor SU5416 on growth and metastasis of experimental rat pancreatic cancer
    血管生成抑制剂SU5416对大鼠胰腺癌生长和转移的抑制作用
    Effects of Angiogenesis Inhibitor SU5416 on Microvessel Density in Rat Model of Pancreatic Cancer
    SU5416对大鼠胰腺癌微血管密度的影响及意义
    Establishment of the model of pancreatic cancer in rats
    大鼠胰腺癌模型制备的实验研究
    Expressions of Skp2 and p27 in Pancreatic Cancer and Non-cancerous Pancreatic Tissues of SD Rats
    大鼠胰腺癌和非癌胰腺组织Skp2和p27表达研究
    Expression of KiSS-1mRNA in pancreatic ductal adenocarcinoma and non-cancerous pancreatic tissues in SD rats
    大鼠胰腺癌和非癌胰腺组织的KiSS-1 mRNA表达
    Objective To observe the effect of somatostatin analogues (octreotide) on the expression of protein and mRNA of somatostatin receptor-2(SST2R) in Sprauge Dawley (SD) rats with pancreatic cancer.
    目的 探索SD大鼠胰腺癌组织SST2R及SST2R mRNA的表达以及外源性生长抑素类似物善得定治疗后其表达量的变化。
    In group B, the expression of SST2R protein and mRNA also decreased significantly after the rats were treated with octreotide (P<0.05, vs pretreatment or group A), but there was no statistic difference 3,7 and 14 days after the octreotide therapy in group B. Conclusions The SST2R protein and mRNA decreased significantly in rat pancreatic cancer tissue.
    B组在治疗后3d、7d、14d时相互比较无显著性差异(P>0.05),但与其治疗前比较有显著性差异(P<0.05)。 结论 SD大鼠胰腺癌组织SST2R mRNA和SST2R的表达量明显减少;
    60 rats with pancreatic cancer were randomly divided into 4 groups: saline group, 5 Fu group, SU5416 group, 5 Fu and SU5416 group. Thirteen weeks after injection, the microvascular density (MVD) of pancreatic cancer was detected.
    将 6 0只SD大鼠胰腺癌模型随机分为 4组 ,分别自腹腔注射生理盐水 (对照组 )、5 氟尿嘧啶 ( 5 FU组 )、SU5 4 16制剂 (SU5 4 16组 )和 5 FU +SU5 4 16联合用药 (联合组 ) ,隔日 1次 ,连续 12周 ,于 13周后处死大鼠 ,剖腹测量其肿瘤的MVD。
    Expression of nerve growth factor messenger RNA in pancreatic cancer tissues in Sprague Dawley rats
    SD大鼠胰腺癌模型组神经生长因子mRNA表达
    A model for pancreatic cancer in SD rat and study on the relationship between expression of IL-8,MCP-1,MIP-1α mRNA and tumor-associated macrophage count
    大鼠胰腺癌模型及其化学趋化因子mRNA表达与肿瘤相关巨噬细胞计数的关系
    Establishment of a model for pancreatic cancer in Sprague-Dawely(SD) rat and study on the relationship among IL-8,MCP-1,MIP-1α mRNA and MC count in the rat pancreatic cancer
    SD大鼠胰腺癌模型及其化学趋化因子mRNA表达与MC计数的关系研究
    Objective To develop a model of pancreatic cancer in common Sprague Dawely rat.Methods The membrane and partial parenchyma (about 1 mm depth) of rat pancreas was opened to put a high dose (9 mg) of dimethylbenzanthracine(DMBA), and then the incision was closed with interrupted sutures.
    目的 研制一种普通大鼠胰腺癌模型。 方法 切开SD大鼠胰腺被膜及部份胰腺实质 ,深 1mm ,置入 9mg的二甲基苯并蒽 (DMBA) ,缝合胰腺被膜。
    Results The prevalence of pancreatic cancer among DMBA-treated rats within 3-5 months was 65% (33/50). Among the 33 rats with pancreatic cancer, 30 rats developed pancreatic ductal adenocarcinomas with glandular duct-like distribution of cancer cells, various sizes of glandular cavities, obvious nuclei heterotpic and atypical cocus of cancer cells under a microscope.
    结果  3~ 5个月内大鼠胰腺癌发生率为 6 5 % (33/ 5 0 ) ,其中 30只为胰腺导管上皮腺癌 ,镜下癌细胞呈腺管样分布 ,腺腔大小不一 ,核异型明显 ,并可见癌细胞巢 ;
    Objective To investigate the effect of ischemia-reperfusion plus particle embolism on the pathology and cell apoptosis of pancreatic cancer (PC) in Sprague Dawely rats.
    目的 探讨缺血再灌注 (I/R )加微球栓塞对病理大鼠的胰腺癌形态学和癌细胞凋亡的影响。
 

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