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squamous cervical carcinoma
    Relationship between apoptosis and clinical biological behavior of squamous cervical carcinoma
    宫颈鳞癌组织中细胞凋亡的表达与临床生物学行为的关系
    The Expression and Significance of p53 Protein in Squamous Cervical Carcinoma
    p53蛋白在宫颈鳞癌中的表达及意义
    Expression and significance of tenascin in human squamous cervical carcinoma
    Tenascin在宫颈鳞癌组织中的表达及其意义
    CD44v6 and E-cadherin expression′s relation with lymph node metastasis of squamous cervical carcinoma
    CD44v6 E-cad表达与早期宫颈鳞癌淋巴结转移的关系
    The expression and significance of the role of differentially expressed gene interleukin 8 of early squamous cervical carcinoma
    早期宫颈鳞癌差异表达基因IL-8的表达及意义
    Expression and significance of KAI1/CD82 and E-Cadherin in Human squamous cervical carcinoma
    KAI1/CD82、E-Cadherin在宫颈鳞癌组织中的表达及其意义
    The Expression and Significance of S100A4 and Adhesion Molecule in Squamous Cervical Carcinoma
    S100A4与黏附分子在宫颈鳞癌中的表达及其意义
    The Expression of Apoptosis Inhibition Gene, Survivin in Squamous Cervical Carcinoma and Its Association with the Expression of P53 and HPV16
    Survivin在宫颈鳞癌组织中的表达及其与p53基因表达和HPV-16感染相关性的研究
    Objective: To study the expressions of gene and protein levels of metastasis-enhancing gene S100A4 and adhesion molecule CD44v6,E-cad,integrinα_vβ_3 in early stage squamous cervical carcinoma (SCC), explore their roles in lymphatic metastasis of SCC.
    目的:分别在基因水平和蛋白水平检测转移促进基因 S100A4 与黏附分子 CD44v6、E-cad、整合素 αvβ3在早期宫颈鳞癌(squamous cervical carcinoma ,SCC)中的表达,探讨其在淋巴结转移中的作用。
    Methods:By using TdT mediated dUTP biotin nick and labeling method(TUNEL)to detect the apoptotic labeling indices(A LI)in 15 cases of normal cervical epithelia,22 cases of cervical intraepithelia neoplasia (CIN)Ⅰ/Ⅱ,16 cases of CIN Ⅲand 52 cases of invasive squamous cervical carcinoma (ISCC)tissues,and using immunohistochemical ABC method to detect the expressions of PCNA(proliferating cell nuclear antigen)in the tissues above mentioned.
    方法 :采用脱氧核苷酸转移酶介导的生物素末端缺口标记法 (TdTmediateddUTP biotinnickendlabeling ,TUNEL)检测 15例正常宫颈上皮 ,2 2例宫颈上皮内瘤变 (CIN)Ⅰ /Ⅱ ,16例CINⅢ及 5 2例浸润性宫颈鳞癌 (ISCC)组织中的细胞凋亡标记指数 (A LI) ,并用免疫组化ABC法检测这些组织中增殖细胞核抗原PCNA的表达。
    Aim:To analysis the relationship between apoptosis and the clinical biological behavior of squamous cervical carcinoma.
    目的 :探讨细胞凋亡在宫颈鳞癌组织中的表达及其与宫颈鳞癌组织学分级、盆腔淋巴结转移及临床分期的关系。
    Methods Apply immunohistochemical ABC method to detect the p53 labelling indices (p53 LI) and p53 positive expression rate in 15 cases of normal cervical epithelia,22 cases of CIN Ⅰand CIN Ⅱ,16 cases of CINⅢ and 52 cases of invasive squamous cervical carcinoma(ISCC) tissues. Results p53 protein was not detected in normal cervical epithelia and CINⅠand CINⅡ.
    方法 采用免疫组化ABC技术 ,观察 15例正常宫颈、2 2例CINⅠ、CINⅡ、16例CINⅢ及 5 2例浸润性宫颈鳞癌 (ISCC)组织中p5 3蛋白表达阳性率及p5 3标记指数 (p5 3 LI)。
    Methods Apply immunohistochemical ABC method to detect the p53 protein labelling indices (p53-LI) and PCNA-LI in 52 cases of invasive squamous cervical carcinoma (ISCC) tissues.
    方法 采用免疫组化ABC法检测 5 2例浸润性宫颈鳞癌 (ISCC)组织中p5 3蛋白标记指数 (p5 3-LI)和PCNA标记指数 (PCNA -LI)。
    Conclusion:EphA2 protein is overexpressed in squamous cell cervical carcinoma, high intensity of EphA2 protein expression in patients with squamous cervical carcinoma reveals a bad prognosis.
    EphA2蛋白表达与宫颈鳞癌患者的年龄、FIGO分期及淋巴结转移无关 ,总生存期在EphA2染色强度 0~ 3级之间差异有统计学意义 (P <0 .0 5 )。 结论 :EphA2在宫颈鳞癌中的高表达预示患者的生存差。
    Objective To study the expression and clinical significance of CD44v6 and E-cadherin(E-cad) in squamous cervical carcinoma.
    目的研究CD44v6与E-钙黏附素(E-cad)在早期宫颈鳞癌中的表达,探讨其在淋巴结转移中的作用及临床意义。
    Methods Twenty-one cases of normal cervical tissue,63 cases of squamous cervical carcinoma without lymph node metastasis,23 cases of squamous cervical carcinoma with lymph node metastasis were detected for the mRNA and protein expression of CD44v6 and E-cad by means of RT-PCR and immunohistochemical method.
    方法采用反转录聚合酶链反应(RT-PCR)与免疫组织化学法对21例正常宫颈上皮、63例无淋巴结转移宫颈鳞癌、23例有淋巴结转移宫颈鳞癌标本中CD44v6、E-cad的mRNA和蛋白表达进行检测。
    Methods:42 patients diagnosed by pathology as squamous cervical carcinoma consisted of 8 case in Ⅱb stage,5 in Ⅲa stage,27 in Ⅲb stage and 2 in Ⅳa stage.
    方法42例宫颈鳞癌患者,均经病理证实,其中Ⅱb期8例,Ⅲa期5例、Ⅲb期27例,Ⅳa期2例。
    Objective To investigate the expression and significance of KAI1/CD82 and E-Cadherin in human squamous cervical carcinoma.
    目的探讨KAI1/CD82、E-Cadherin在宫颈鳞癌中的表达及其意义。
    Methods The expressions of KAI1/CD82 and E-Cadherin were examined respectively by immunohistochemical S-P method in 10 cases of normal cervical tissue,15 cases of atypical hyperplasia of cervical epithelia and 64 cases of squamous cervical carcinoma. We analyzed statistically the correlation between the immunohistochemical results and the clinicopathological features.
    方法采用免疫组化S-P法分别检测KAI1/CD82、E-Cadherin在10例正常宫颈组织、15例不典型增生宫颈组织及64例宫颈鳞癌中的表达,分析其表达结果与临床病理特征的关系。
    Pretreatment serum hemoglobin level as a predictive factor of response to neoadjuvant chemotherapy in patients with locally advanced squamous cervical carcinoma: A preliminary report
    治疗前血清血红蛋白水平作为预测局部晚期宫颈鳞癌对新辅助化疗的反应指标的初步报道
 

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