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injured control group
    To explore the effect of Ligustrazine on the expression of adherent molecule of bone marrow cells in acute radiation injured mice, 27 Kunmin mice were randomly divided into 3 groups: Normal group, acute radiation injured control group, Ligustrazine group.
    为探讨急性放射损伤小鼠骨髓细胞粘附分子表达及川芎嗪对其影响,将27只昆明小鼠平均分为3组:正常组,急性放射损伤对照组,川芎嗪组。
    The rats in the hyperbaric oxygen treatment group and injured control group were killed at hour 48 after injury.
    高压氧治疗组、损伤对照组大鼠均在受伤后48h处死。
    Results Compared to the spinal cord injured control group, the expression of NOS in the anterior horn of the transected spinal cord was increased in embryonic transplanted group (P<0.01), the locomotor functions of the transplated rats improved as well compared to the injured control.
    结果 胚胎大鼠脊髓移植后可以使全横断脊髓前角内NOS表达增加 ,与损伤对照组比较有显著性差异 (P <0 .0 1) ; 大鼠后肢的自主运动功能恢复好于损伤对照组
    METHODS: The experiment was done in the Animal Experiment Center, Southern Medical University from April to May 2003. Forty clean grade male SD rats were selected and divided randomly into injured control group, aminoguanidin group, 7-nitroindazole (7-NI) group and normal control group with 10 in each group.
    方法:实验于2003-04/05在南方医科大学动物实验中心完成。 选取清洁级雄性SD大鼠40只,随机分为损伤对照组、氨基胍组、7-硝基吲唑组和正常对照组,每组10只。
    ① In the normal tissue there was the content of nitrogen monoxide and NOS, which showed the trend of increasing after injury. That in the injured control group was the most significant, and the difference was significant compared with other 3 groups (P < 0.05).
    ①正常组织中即存在一氧化氮含量和一氧化氮合酶,损伤后呈升高趋势,以损伤对照组最明显,与其他3组相比差异明显(P<0.05)。
    ② The action potential in the 7-NI group and aminoguanidin group had significant recovery than that in the injured control group, while there was little clear wave form appeared in the injured control group;
    ②7-硝基吲唑组和氨基胍组动作电位较损伤对照组有明显恢复,而损伤对照组则基本没有明确的波形出现;
    The latency and amplitude of vibration in the 7-NI group, aminoguanidin group and normal control group had significant difference compared with the injured control group (P < 0.05), while there was insignificant difference between the 7-NI group and aminoguanidin group.
    7-硝基吲唑组和氨基胍组及正常对照组潜伏期和振幅比损伤对照组有明显差异(P<0.05); 7-硝基吲唑组和氨基胍组两组之间比较则差异不明显。
    ③ There were different levels of changes of MRI signal (T2), e.g. the occipitofrontal diameter of spinal cord became narrow, intensity of signal increased etc. In the injured section of spinal cord tissue there was wide degeneration and fibrosis, normal signal continuous break, especially it was most significant in the injured control group, while there were continuous signals in the treatment group.
    ③伤后MRI信号(T2)均存在不同程度的改变,如脊髓的前后径变窄,信号强度增高等,伤段脊髓组织存在广泛的变性和纤维化,正常信号连续性中断,尤以损伤对照组组最明显,而治疗组则表现有比较连续的信号。
    ④ The scores in the aminoguanidin group and the 7-NI group had significant increase compared with the injured control group, while the effect of the former was more significant, and it was insignificant difference compared with the normal control group.
    ④氨基胍组和7-硝基吲唑组与损伤对照组相比,BBB评分结果明显提高,而以前者作用更加明显,并与正常对照组的差异不明显。
    ① Two hours after spinal cord injuries of rats in injured control group and electro-acupuncture group, score of motor function and critical angle of ram which was measured with modified Rivlin method were decreased remarkably;
    方法:损伤对照组和电针治疗组制备脊髓损伤模型,假手术组仅作椎板切除。
    METHODS: The experiment was performed at the Department of Pathology,Norman Bethune University of Medical Sciences from June 2004 to June 2005. ①A total of 60 adult SD male rats were selected and divided into 3 groups randomly: hyperbaric oxygen treatment group,injured control group and sham operation group with 20 in each group.
    方法:实验于2004-06/2005-06在白求恩医科大学病理科完成。 ①选择成年SD雄性大鼠60只,随机数字表法分为高压氧治疗组、损伤对照组、假手术组,20只/组。
    ②Head injury models were established in the hyperbaric oxygen treatment group and injured control group. After opening bone window,consistent contusion and laceration of brain at right parietal lobe was established with free fall method,with the impact of 50 g×13 cm.
    ②高压氧治疗组、损伤对照组大鼠建立颅脑损伤模型,开放骨窗后采用自由落体法造成右顶叶较为一致的脑挫裂伤,冲击力为50g×13cm。
    Those in the injured control group did not receive hyperbaric oxygen treatment.
    损伤对照组不进行高压氧治疗。
 

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