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    A kind of device to measure oxygen permeability of the copolymer hydrogel membrane was designed, and oxygen permeability of the copolymer hydrogel were measured by this device as well.
    采用自行设计的水凝胶膜透氧性能测定装置,用测氧仪测定不同渗透时间下氧气的渗透量,研究了共聚物水凝胶角膜接触镜材料的透氧性能。
    Compared with the measured data, relative error of the estimated total amount leached N were 0.99 and 19.62%, respectively, with and without considering the transient water condition and the N transformations.
    (3)与总输入量相比,空间上平均的土壤水渗透量和硝态氮淋失量不高,而某些采样点处土壤水渗透量和硝态氮淋失量大大高于均值,是农田管理和环境监测的脆弱带;
    The solubility index was obtained from DSC analysis to predict the thermoactivity and permeation competent of VIN and linear relationship was found between the permeation amount and solubility index (r>0.9) .
    以DSC法测定了Gelva 737、E100、国产丙烯酸树脂Ⅳ号等压敏胶的溶解度指数,分别建立了溶解度指数与12h、24h药物经皮累积渗透量之间的相关性(r>0.9),并用此参数预测药物在压敏胶中的热力学活性及经皮渗透行为,最后选择Eudragit E100作为VIN透皮贴剂的压敏胶;
    The EIS results showed that charge transfer resistances and the inductance atlow frequency decreased with the working voltage decreasing at differenttemperatures, whereas the internal resistance increased. The charge transferresistance and mass transport resistance of oxygen reduction reaction increasedwith the increment of methanol permeation.
    还利用EIS 分析了甲醇渗透对阴极氧还原反应和氧气传质的影响,结果表明氧还原反应的电荷转移电阻和氧气传质阻抗随甲醇渗透量的增加而增大。
    When the boards are compressed certainly after impregnated with PF resin, the surface density is higher than the core’s with the concentrations of PF resin and the compression ratio, it results in the surface hardening.
    树脂浓度较高时由于粘度增加,渗透量和增重率、增容率并不增大,速生杨木材以PF树脂浸渍取20%-30%浓度较为适宜。 为降低浸渍处理的成本,可在树脂水溶液中填加一定浓度的填料,10%左右填料对浸渍效果不会产生明显影响。
    Sorption method and optimal approach were used to measure and calculate moisture increase values and temperature, by which the relational expressions among thermal diffusion coefficient, moisture content and temperature were obtained.
    采用加湿法,通过比较计算渗透量和实验渗透量及计算温度和实验温度的数值,利用多变量寻优的方法得到了热质扩散系数与湿含量和温度之间的关系式。 在得到湿分扩散系数和热质扩散系数关系式后,对多孔物料湿热灭菌的热量质量传递模型进行了数值计算和实验验证。
    2. 2% Azone can enhance the absorption of Dichlofenac across skin. The drug concentration change through skin under the effect of Azone is 3 to 5 times than common.
    2.月桂氮革酮(Azone)能促进双氯灭痛的透皮吸收,使透皮吸收药物的累积渗透量提高3-5倍。
    Chitosan is able to increase the uptake of insulin, LA;
    壳聚糖能够促进胰岛素等药物的渗透量,TMC、CEC为壳聚糖的衍生物,推测它们有着类似于壳聚糖促吸收的功能。
    Horizontal and vertical diffusion cell was used to evaluated the permeability of HQ gels by the skin of rat. The result showed that the permeability was poor. It is available to the treatment of hyperpigmentation.
    用卧式扩散池和直立式扩散池法评价氢醌凝胶剂体外经大鼠皮肤渗透的性质,结果表明,pH对氢醌的透皮吸收影响不大,氢醌渗透量低,不会影响药物疗效,有利于色素沉着疾病的治疗。
    Horizontal diffusion cell was used to screen the permeation promoters in order to improve the drug permeation.
    为了提高药物的经皮渗透量,本文用水平扩散池对几种常用的促渗剂进行了筛选。
    The total flux of permeance is 1.16kg/m2h-1 and the selectivity is 1054 under the best operating condition. The preparation rules of NaA zeolite under microwave heating were investigated by orthogonal experiments.
    将所合成的NaA分子筛膜应用于乙醇/水渗透蒸发实验,考察了温度及压差对其性能的影响,得到了膜管在最佳工艺条件下的渗透量为1.16kg/m~2h~(-1),乙醇与水的分离因数为1054。
    The screening penetration test in vitro help us to find the most active enhancer, which cause 5.01-fold cumulative amount and 5.2-fold Kp increase contrast to basic formulation.
    而且筛选出对其透皮吸收相当有效的促渗剂,6小时的累积渗透量Q比基础处方提高5. 01倍,渗透系数Kp提高5. 2倍。
    Based on the study above, the optimal concentration of this enhancer was determined. The result showed that the accumulative permeation of Naloxone Hydrochloride with this enhancer was 2-3 times higher than that without enhancer.
    研究结果显示:选定的吸收促进剂可使盐酸纳洛酮透过羊鼻黏膜的累积渗透量增加2-3倍。
    8. The calculated cumulative transdermal amount of propranolol chloride from the artificial neural networks is in good accordance with the respective experimental one.
    8、神经网络法计算得到的盐酸普蔡洛尔累积渗透量一与实测值一致。
    Liensinine in transdermal patch was permeated at zerorate,and the cumulative penetration percentage of Liensinine amounted to 18.74%. Theparameters of patch comes up to the standard of the Pharmacopoeia of People’s Republicof China(2000).
    并对巴布剂进行了体内外评价,结果显示,24h 药物累积渗透量达 18.74%,各项指标符合中国药典(2000版)巴布膏剂标准。
    Experiment date indicate that electroporation can effectively enhance transport of FD-4 and FD-20s, and also find that voltage, capacitance, molecular weight and different part affect the substance transport.
    实验结果最终发现电穿孔能有效促进FD-4和FD-20s的经皮转运,从而为电穿孔转运大分子的生物药物提供可寻依据。 并且发现电压、电容、分子量、不同部位都对物质的经皮转运渗透量有影响。
    All data collected were analyzed with SPSS 11.5 software. Peak area(A) — concentration(C) standard curves were obtained. Calculate Q (accumulativepermeation quantity) at each correspond time.
    采用SPSS11.5版本统计软件求得新乌头碱峰面积值(A)-浓度(C)标准曲线,并计算出各取样点浓度以及各时间点(t)对应的累积渗透量(Q)。
    It is important to improve drug transdermal permeation.
    在临床上,提高物质的经皮渗透量是非常重要的。
    In this paper, we use high pulse electroporation to promote the insulin's transport through epidermis.
    本文主要研究了高压脉冲电场促进胰岛素经皮渗透的作用,并分析了胰岛素的经皮渗透量随时间的变化规律,以及脉冲电压、能量对胰岛素经皮渗透量的影响,为电穿孔技术促进胰岛素经皮给药的临床应用提供了可能。
    1. Insulin permeation flux under electroporation pulse: applied the pulse voltage to the both side of the skin, then measured the concentration of insulin in the receptor room in different sampling times, so that we can calculate the flux of the insulin which transport through the skin.
    1.高压电脉冲下胰岛素的经皮渗透量:通过在皮肤两侧施加脉冲电压,用高效液相仪测量接受室的胰岛素浓度,并获得胰岛素的经皮渗透量
 

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