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    A Mathematic model for subtyping schizophrenia 1.Establishment of the model
    精神分裂症亚型划分的数学模型一、数学模型的建立
    Changes of subtypes and symptoms of schizophrenia over 20 years
    近20年来精神分裂症亚型及症状变迁
    Association between polymorphism in the dopamine D_3 receptor gene and the sutypes of schizophrenia and efficacy of risperidone
    多巴胺D_3受体基因多态性与精神分裂症亚型及利培酮疗效相关性分析
    (3)There were no significant differences in the distributions between the positive symptom group or the negative symptom group and the healthy controls,neither between the positive group and the negative group( Z <1.96, P >0.05).
    (3)阳性症状和阴性症状两类精神分裂症亚型分别与健康对照组相比 ,或两个亚型间比较 ,同样在DAT1基因多态性分布上无差异 (Z值小于 1.96 ,P >0 .0 5 )。
    It was found that there was no significant relationship between the subtype of shizophrenia and the distribution of blood groups(P >0. 05),no obvious difference from distributing frequence of normal blood group(P> 0. 05).
    结果,精神分裂症亚型与ABO的血型分布无明显关系(P>0.05),与正常群体血型分布频率也无明显差异(P>0.05)。
    Conclusion:There is an association between the DRD 3 Ser9Gly gene polymorphism and the subtypes of schizophrenia. No association exists between the Ser9Gly polymorphism and the efficacy of risperidone.
    结论DRD3受体基因第一外显子Ser9Gly多态性可能与精神分裂症亚型相关,而与患者对药物的反应不相关。
    and it doesn′t have effect on schizophrenia genetic background.
    该多态性与精神分裂症亚型不存在相关性,对精神分裂症患者遗传背景也没有影响。
    CSF Homovanillic Aeide Level of Positive,Negative Schizophrenia Patients and Normal Controls
    精神分裂症亚型与脑脊液中高香草酸水平的探讨
    The variations of P300 subcomponents amplitudes might be the trait markers of scizophrenia 2. These findings suggest that different subtype of schizophrenics possibly display different basi s of neurobiology.
    2.氏. 、氏波幅所显示出的不同亚型间的差异提示:精神分裂症亚型间存在不同的病理学基础。
    2)For these Chinese Han schizophrenia in this study,we can not assure the association between Val158Met polymorphism of COMT gene and schizophrenia. On the other hand,we can not exclude that the Val158Met polymorphism of COMT gene affect clinical symptoms in schizophrenia,or associate with subtype of schizophrenia.
    2 )对于本研究中的汉族精神分裂症来说 ,尚不能确定COMTVal15 8Met多态性与精神分裂症有关联 /连锁 ,但不能排除它在精神分裂症临床症状中的作用以及与精神分裂症亚型关联或连锁的可能性
    Conclusions Our findings support that schizophreniform psychosis is one of the subgroups of schizophrenia.
    结论 支持分裂样精神病为精神分裂症亚型的分类方法。
    Conclusion The findings suggest that there are some biological differences between negative and positive schizophrenics and antipsychotic drugs might improve some cerebral cortex functions.
    结论 阴性、阳性精神分裂症亚型之间可能有不同的神经生物学基础 ,抗精神病药物可以改善某些大脑皮质机能。
 

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