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colorectal adenocarcinoma
    But the frequency of slow acetylator genotype was increased significantly in patients with colorectal adenocarcinoma compared with controls (42.8% vs 33.7%,P=0.033,OR=1.576,95%CI:1.037—2.396).
    但与正常对照组相比,结肠腺癌患者中慢型乙酰化基因型频率增高(42.8%比33.7%,P= 0.033,OR=1.576,95%CI:1.037~2.396)。
    The in vitro and in vivo chemotactic effect on immune cells by hMIP-1β gene transfected murine colorectal adenocarcinoma CT26 cells
    hMIP-1β基因转染小鼠结肠腺癌CT26细胞对免疫细胞的体内外趋化作用
    The expression of p27~(kip1) in colorectal adenocarcinoma and the correlation with the clinicopathological features
    结肠腺癌组织p27~(kip1)表达水平及与临床病理因素的关系
    Association between N-acetyltransferase 2 gene polymorphisms and genetic susceptibility to sporadic colorectal adenocarcinoma
    N-乙酰基转移酶2基因多态性与结肠腺癌易感性的关系
    The expression of CD44v6 in the high and middle differentiated colorectal cancer were 45.8% (11/24) and 68.7% (11/16) respectively, which had significant difference (P<0.05), but which had no striking difference from the expression in human colorectal adenocarcinoma (P>0.05).
    在高、中分化腺癌组织中 ,CD44 v6阳性率分别为 45 .8%(11/ 2 4)和 6 8.7%(11/ 16 ) ,有显著性差异(P<0 .0 5 ) ,但在直肠腺癌组织与结肠腺癌组织间表达无显著性差别 (P>0 .0 5 ) .
    Objective To analyze the association of genetic polymorphism of Glutathione S transferase (GST) M1, T1 and N acetyltransferase 1(NAT1) with genetic susceptibility to sporadic colorectal adenocarcinoma (SCRAC).
    目的 探讨谷胱甘肽S 转移酶 (GST)M 1、T1和N 乙酰化转移酶 1(NAT1)基因多态与散发性结肠腺癌 (SCRAC)遗传易感性的关联。
    Objective To investigate the expression of p27kip1 protein in colorectal adenocarcinoma and relationship with the biological behaviors.
    目的观察结肠腺癌组织p27kip1表达水平,探索其与肿瘤分化程度等临床病理因素间的关系。
    Conclusion The decrease of p27kip1 expression may be involved in the malignant transformation of colorectal epithelial cells to colorectal adenocarcinoma.
    结论结肠腺癌组织p27kip1表达水平降低,且与肿瘤恶性程度、侵袭能力、淋巴结转移有关,可作为判定结肠癌恶性程度及预后的一个指标。
    Relation between genetic polymorphism in xenobiotica metabolizing enzymes and risk of sporadic colorectal adenocarcinoma
    毒物代谢酶基因多态性与结肠腺癌易感性关联
    Objective\ To analyze the role of E-cadherin(E-cad) and associated protein α-catenin(α-cat) in lymph node metastasis of colorectal adenocarcinoma.
    目的 比较 E-钙粘附蛋白与相关蛋白α-连接蛋白在结肠腺癌的表达及在淋巴结转移中的作用。
    Objective To investigate the transcription level and protein expression of HIF-1α and VEGF in SW480 cell line and colorectal adenocarcinoma, and to determine whether HIF-1α plays a role in angiogenesis through its regulation of VEGF. Methods HIF-1α mRNA expression was analyzed by in situ hybridization.
    目的 观察低氧培养条件下人结肠腺癌SW4 80细胞及人结直肠腺癌组织中缺氧诱导因子 1α(HIF 1α)mRNA、蛋白表达 ,探讨HIF 1α在结直肠腺癌中的表达及在肿瘤血管形成中的作用。
    Methods The colonscopic characteristics of the 1013 cases of colorectal adenoma and 194 cases of colorectal adenocarcinoma were analyzed in our hospital examined patients from Jan. 2000 to Jan. 2005. Results The rates of the adenoma and adenocarcinoma in left colon were significantly higher than that in right colon;
    方法回顾我院2000年1月~2005年1月经结肠镜检查和活检病理证实的大肠散发性腺瘤1013例和结肠腺癌194例的结肠镜下特点。
 

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