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    Study on Abzyme with Activity of Glutathione Peroxidase(GPX) Preparation and Chemical Mutation of Monoclonal Antibodies
    具有谷胱甘肽过氧化物酶(GPX)活力的抗体酶研究──单克隆抗体的制备及化学诱变
    Methods The contents of vitamin C,vitamin E in plasma,the activities of superoxide dismutase(SOD),catalase(CAT),glutathione peroxide(GPX) and the content of lipid peroxide(LPO) in erythrocytes were examined by spectrophotometry in welders.
    方法采用分光光度法检测电焊作业者(WOs)血浆维生素C(VC)、维生素E(VE)含量,红细胞超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GPX)活性和过氧化脂质(LPO)含量。
    MethodsAn animal model of rat with hyperthyroidism was established and hepatic SOD,MDA and GPX were detected by enzymology method.
    方法建立甲亢大鼠模型,采用酶法测定甲亢组和正常组大鼠肝脏匀浆中超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GPX)的活性及丙二醛(MDA)的含量。
    Preparation and Property Studies on Modified Hyaluronic Acid as Novel Glutathione Peroxidase(GPX) Mimic
    以透明质酸为骨架的新型谷胱甘肽过氧化物酶(GPX)模拟酶的制备及性质研究
    Parameters selected in the study including: liver antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), reduced glutathione (GSH) and glutathione S-transferase (GST) were determined, brain acetylcholinesterase (AChE) and liver inducible nitric oxide synthase (iNOS) activities were also measured;
    在实验中检测的指标包括,抗氧化酶指标:超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GPx)、谷胱甘肽(GSH)、谷胱甘肽硫转酶(GST)、乙酰胆碱脂酶(AChE)和诱导型一氧化氮合酶(iNOS);
    Compared with group NO , NI and LI , testis glutathione peroxidase (GPx) activity in group HO and HI strikingly increased (p<0. 01).
    HO和HI两组大鼠睾丸谷胱甘肽过氧化物酶(GPx)活性与NO、NI和持续性低碘组(LI)相比显著升高(p<0.01);
    Some physiological indexes were measured in experimental regime,including LCso>oxygen consumption rate,ammonia-N excretion rate,AchE and Na=+,K+-ATPase activitiesO2 and some antioxidant enzymes (such as superoxide dismutase,catalase,glutathione peroxidase, glutathione S-transferase and glutathione reductase) activities.
    所测定的生理指标包括耗氧率、排氨率、乙酰胆碱酯酶(AChE)、Na~+,K~+-ATPase、超氧阴离子自由基(O_2~-)、超氧化物歧化酶(SOD)、过氧化氢酶(CAT)、谷胱甘肽过氧化物酶(GPX)、谷胱甘肽转硫酶(GST)和谷胱甘肽还原酶(GR)。
    Objective:To study the effect of beta-carotene(BC) on adriamycin(ADM)induced changes of expression of manganese superioxide dismutase(Mn SOD)mRNA,copper-zinc superioxide dismutase(Cu-Zn SOD) mRNA and glutathioneperoxidase(GPx) mRNA in myocardial tissue of rats,and to explore themechanism of BC antagonizing the reduced activities of Mn SOD、Cu-Zn SOD、GPx in myocardial tissue of rats induced by ADM.
    目的:研究β-胡萝卜素(BC)对阿霉素(ADM)致大鼠心肌组织的铜锌超氧化物歧化酶(Cu-Zn SOD)mRNA、锰超氧化物歧化酶(Mn SOD)mRNA、谷胱甘肽过氧化物酶(GPx)mRNA 表达改变的影响,探讨BC 拮抗ADM导致心肌组织的Mn SOD、Cu-Zn SOD、GPx 活性降低的机制。
    The levels of the membrane Ca~2, Mg~2-Adenosine Triphosphatase (Ca~2, Mg~(2+)-ATPase) and the cytoplasm reduced Glutathione (GSH) and Gluthione Peroxidase (GPx) in the rat livers were studied in various age groups.
    本文观察了不同年龄组大鼠肝细胞膜中钙镁-腺苷三磷酸酶(Ca~(2+),Mg~(2+)-ATPase)的活性,同时测定胞液中还原型谷胱甘肽(GSH)和谷胱甘肽过氧化物酶(GPx)的含量。
    The concentrations of LPO, GPX and V-E in blood were determined for 56 schizophrenics and 42 normal controls. The results showed that the concentration of LPO of the patients was significantly higher than that of the controls (P<0.05) and the concentrations of GPX and V-E of the patients were obviously lower than that of the controls (P<0.01).
    对56例精神分裂症患者和42例正常对照组的血清过氧化脂质(LPO)、谷胱甘肽过氧化物酶(GPX)和维生素E(VE)水平进行了测定,结果表明:LPO含量明显高于对照组(P<0.05),GPX活性和VE含量明显低于对照组(P<0.01);
    To evaluate the influence of selenium (Se)-supplementation on glutathione peroxidase (GPX) protein contents in erythrocyte, residents aged 14-16 yr from a 1ow-Se Keshan disease area were given orally 200μg Se daily as Se-yeast or sodium selenite for 12 wk, Se contents, GPX activities and GPX protein levels were measured.
    给克山病病区14岁~16岁居民每日口服200μg硒(亚硒酸钠或硒酵母)12周测定红细胞硒含量、谷胱甘肽过氧化物酶(GPX)活性和GPX蛋白水平,以探讨补硒对人红细胞GPX蛋白的影响。
    To investigate the effects of selenium (Se)supplements on the red cell immune adherence (RCIA)function of patients with Kashin-Beck disease(KBD), KBD patients aged 13~16 years were given orally 200μg Se daily as sodium selenite or Seyeast for 12 weeks, and their erythrocyte Se contents and activities of glutathione peroxidase (GPX), RCIA function,serum RCIA regulatory functions and circulating immune complexes(CIC)contents were determined.
    给13~16岁大骨节病患者每日口服200μg亚硒酸钠硒或硒酵母硒12周,测定红细胞硒含量和谷胱甘肽过氧化物酶(GPX)活性、红细胞免疫粘附(RCIA)功能、血清RCIA调节功能和循环免疫复合物(CIC)含量,以探讨补硒对大骨节病患者RCIA功能的影响。
    The levels of serum lipid peroxides(LPO),water-soluble fluorescence substance(WSFS),glutathione peroxidase(GPX)and vitamine E(VE)were studied on 31 patients with delayed encephalopathy after acute carbon monoxide poisoning(DEACMP).
    测定了31例急性一氧化碳中毒后迟发性脑病患者血清过氧化脂质(LPO)、水溶性脂质过氧化物(WSFS)、谷胱甘肽过氧化物酶(GPX)、维生素E(VE)的含量,并与健康者作了比较。
    We adopted the model of langendorff perfusion in order to observe superoxide dismutase(SOD),Glutathione peroxidase(GPX), Lactate dehydrogenase(LDH), Cretine phosphokinase (CK),malondialdehyde (MDA)and ultrastructure of oxygen free radicals(OFR)cleaning enzymes during ischemia reperfusion of myocardial injury.
    采用Langendorff灌注模型,对心肌缺血/再灌注损伤中氧自由基清除酶系统超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GPx)和乳酸脱氢酶(LDH)、磷酸肌酸激酶(CK)、丙二醛(MDA)、超微结构的变化及硒的抗氧化效应进行了观察。
    12 weeks later, blood selenium,plasma GPX and liver 5′ DI were assayed.
    12周后测血硒、血浆谷胱甘肽过氧化物酶(GPX)以及肝5′-脱碘酶活性。
    Objective To investigate the relationship of superoxide dismutase (SOD), lipid peroxide (LPO) and glutathione peroxidase (GPx) with periodontal diseases.
    目的探讨超氧化物歧化酶(SOD)、脂质过氧化物(LPO)和谷胱甘肽过氧化物酶(GPX)与牙周组织疾病的关系。
    The levels of total plasma homocysteine(tHcy),the concentrations of serum folate and the activites of erythrocytic superoxide dismutase(SOD) and glutathione peroxidase(GPX) were measured.
    测定血浆总 Hcy(t Hcy)浓度、血清叶酸浓度及红细胞超氧化物歧化酶 (SOD)和谷胱甘肽过氧化物酶 (GPX)活力。
    Boleophthalmus pectinirostris were exposed to BaP containing seawater at concentrations of 0.05, 0.20 and 0.50 mg/L for 1 week.
    研究大弹涂鱼 (Boleophthalmuspectinirostris)暴露于 0 .0 5、0 .2 0和 0 .50mg/L不同质量浓度苯并(a)芘 (BaP)溶液中 1周 ,其肝脏谷胱甘肽过氧化物酶 (GPx)活性的变化。
    Enzymatic detoxication system includes supero xide dismutase (SOD),ascorbate peroxidase (APX),catalase (CAT) and glutathione peroxidase (GAX);
    酶促脱毒系统包括超氧化物歧化酶 (SOD)、抗坏血酸过氧化物酶 (APX)、过氧化氢酶 (CAT)和谷胱甘肽过氧化物酶 (GPX)等。
    TBA method, nitrate reductase method, DTNB method and pyrogallol autoxidation method were used to determine the content of lipid peroxide (LPO) and nitric oxide (NO), the activity of glutathione peroxidase (GPx) and superoxide dismutase (SOD) in myocardium, respectively.
    分别用TBA法、硝酸还原酶法、DTNB法、邻苯三酚自氧化法测定心肌的脂质过氧化物 (LPO)含量、一氧化氮 (NO)含量、谷胱甘肽过氧化物酶 (GPx)活性、超氧化物歧化酶 (SOD)活性 ;
 

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