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    OBJECTIVE To observe the expression of NF-κB p65 at different periods in renal tubulointerstitium and the effect of atorvastatin on the expression of NF-κB p65 in unilateral ureteral obstruction(UUO) model rats.
    目的观察单侧输尿管梗阻(UUO)大鼠肾小管间质核转录因子-κB(NF-κB)的动态表达及阿托伐他汀对其的影响。
    Mechanism of rosiglitazone anti-fibrosis effect on unilateral ureteral obstruction rats
    罗格列酮对单侧输尿管梗阻大鼠肾间质纤维化的保护作用及其机制
    Expression of TGF-β_1 and TIMP-1 and Effects of Atorvastatin in Rats After Unilateral Ureteral Obstruction
    阿托伐他汀对单侧输尿管梗阻大鼠肾间质中TGF-β_1及TIMP-1表达的影响
    Effects of Vitamin K_3 on action potential of Ureteral Smooth muscle and Urodynamics in rabbits
    维生素K_3对家兔输尿管平滑肌动作电位和尿路动力学的影响
    Effect of fosinopril and losartan on the expression of TGF in rat kidney after unilateral ureteral obstruction
    福辛普利及氯沙坦对单侧输尿管梗阻大鼠肾脏TGF-β_1表达的影响
    Effect of Atorvastatin on the activity of mitogen-activated protein kinase p38 in renal tubular interstitium of rats with unilateral ureteral obstruction
    阿托伐他汀对单侧输尿管梗阻大鼠肾小管间质丝裂原活化蛋白激酶p38活性的影响
    Effects of Atorvastatin on Expression of NF-κB in Unilateral Ureteral Obstruction Rats
    阿托伐他汀对单侧输尿管梗阻大鼠肾小管间质中核因子-κB表达的影响
    Effects of Artorvastatin on ICAM-1 and P-selectin in Rat Renal Interstitial after Unilateral Ureteral Obstruction
    阿托伐他汀对单侧输尿管梗阻大鼠肾小管间质ICAM-1、P-选择素表达的影响
    Experimental Investigation of the Protective Effect of Sodium Ferulate on Rat Kidney after Unilateral Ureteral Obstruction
    阿魏酸钠对单侧输尿管梗阻大鼠肾脏保护作用的实验研究
    Influence of Irbesartan on the Expression of CTGF and ILK and Its Relationship with Epithelial-mesenchymal Transition in Mice with Unilateral Ureteral Obstruction (UUO)
    厄贝沙坦对单侧输尿管梗阻小鼠肾脏CTGF、ILK表达的影响及意义探讨
    unilateral ureteral obstruction were used by ligating the left uretera,the sham group take the seem opration except for not ligating the left uretera.
    10%水合氯醛(4ml/kg)腹腔注射麻醉后行左侧输尿管结扎离断术,建立单侧输尿管梗阻模型,假手术组不结扎离断左侧输尿管,其余操作相同。
    The purpose of this study was to investigate the influence of Irb on the expression of recently recognized connective tissue growth factor (CTGF) and integrin-linked kinase (ILK) and its relationship with EMT in mice with unilateral ureteral obstruction (UUO). METHODS: UUO model was made as previously reported.
    本研究通过单侧输尿管梗阻(UUO)模型观察AngⅡ1型受体拮抗剂厄贝沙坦(Irbesartan, Irb)对肾组织结缔组织生长因子(connective tissue growth factor, CTGF)和整合素连接激酶(integrin-linked kinase, ILK)表达的影响,并探讨其与肾小管上皮间充质转化的关系。
 

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