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    The Experimental Study of the Effection of Compound Salviol Miltirone in Penis Erection
    丹参混合液诱发阴茎勃起的实验研究
    Three groups of emasculated rats were administered withsheep placenta-pearl capsule 0.84g/kg, 0.42g/kg and 0.21g/kg respectivelyby i.g.
    羊胎素-珍珠胶囊按0.84g/kg、0.42g/kg、0.21g/kg分高、中、低三个剂量组灌胃给药20d后,观察其对去势大鼠阴茎勃起潜伏期及对包皮腺、精液囊和前列腺重量的影响。
    Macrophage phagocyticfunction expurgation indexes of mice were increased distinctly by threedose groups sheep placenta -pearl capsule (P<0.01 、 P<0.01 andP<0.05) .
    高、中、低剂量组羊胎素-珍珠胶囊使小鼠血清溶血素明显升高(P<0.01和P<0.05),有剂量-反应关系。 高、中、低剂量组羊胎素-珍珠胶囊使去势大鼠阴茎勃起潜伏期明显缩短(P<0.01);
    ResultsDZKC 0.2 , 0.6 and 2 g/kg oral for 21 days shorted the stimulation time for erection in the male rats,but not significantly.
    结果杜仲康茶0.2、0.6和2g/kg灌胃有使阴茎勃起潜伏期缩短的趋势,但是与对照组相比无显著性差异。
    The positive reaction of NOS and AchE was significantly stronger in DD group than in group DM (P<0.05).
    DD组阴茎勃起潜伏期明显短于DM组,差异显著(P<0.05)。
    Studies of the Pharmaceutical Action Mechanism of Icariin on Penile Erection
    关于淫羊藿甙对阴茎勃起作用机制的研究
    Conclusion: Icariin could enhance the normal rat's penis erection function in a dose-depended manner, which was related with NO-cGMP signal pathway.
    结论:淫羊蕾普可以呈浓度依赖性地增强大鼠阴茎勃起功能,该作用与NO一cGMP信号通路有关;
    Penile erection is homodynamic procedure mediated by neuron-endocrine system,and the relaxation of smooth muscle of the corpus cavernosum(CC) and its associated arterioles plays a key role in penile erection.
    阴茎勃起是阴茎海绵体及相关动静脉血管的血液动力学变化,勃起过程中阴茎动脉和海绵体平滑肌的松弛作用起着关键作用,而且阴茎勃起过程受神经-内分泌系统的调节。
    Recent researches have indicated that NO-cGMP signaling pathway played the most important role in regulation of penile erection.
    近来的研究表明,一氧化氮-环磷酸鸟苷(NO-cGMP)信号通路在阴茎勃起过程中起重要的调控作用。
    It can enhance the sexuality and reinforce erection of rats too. The results suggest that the effect mechanism of incariin have great relation not only to its increasing the male hormone level and the content and activity of monoamine neurotransmitter in rats ' hypothalamus but also to its improving the erectile tissue structure, increasing the content of eNOS and decreasing the content of ET-1 expressed in the corpus cavemosum of the rats' penis.
    结论:淫羊藿苷可显著改善老龄大鼠的性活动能力,提高性欲,增强勃起,其作用机理与提高机体雄激素水平、提高下丘脑单胺类神经递质DA和5-HT含量、改善阴茎勃起组织结构、提高阴茎海绵体eNOS含量、降低ET-1含量有关。
    It could shorten the erectile latent period of aged rats (P<0.05) and increase the erectile intensity (P>.05);
    用药后可缩短老龄各组阴茎勃起潜伏期(P<0. 05) ; 对于勃起强度有一定的增加(P>. 05) 。
    In castrated rats,the pill increased the weight of seminal vesicle,prostate and preputial glands,and shortened the latent period of penis erection induced by electric stimulation.
    使去势大鼠精囊、前列腺、包皮腺明显增重; 缩短去势大鼠电刺激阴茎勃起的潜伏期;
    The results indicated that LHC could increase the weight of prostatic capsule, spongy body and levator ani muscle of the unsex rats, enhance the serum testosterone, shorten the penil erection period.
    实验结果表明,龙马回春胶囊能明显增加去势大鼠的前列腺贮精囊、海绵球肌及肛提肌重量,提高血清睾酮水平,缩短阴茎勃起潜伏期;
    but penis was successfully erected by injecting CSM, the doses of papaverine were significantly decreased in this process.
    (2 )丹参混合液能成功诱发阴茎勃起且可显著降低罂粟碱的剂量 ,而且单纯在罂粟碱中加入丹参或酚妥拉明并不能减少罂粟碱的用量。
    Results: Gushen capsule can decrease serum and lipid peroxidation in liver obviously and increase activity of red blood cell and SOD in liver, promote specific and nonspecific immune function, shorten incubation period of priapism and ejaculation; increase the times of ejaculation.
    结果 :固肾胶囊可使血清及肝组织中过氧化脂质明显降低 ,增强红细胞及肝中SOD的活性 ,增强机体的特异性及非特异性免疫功能 ,缩短阴茎勃起潜伏期及射精潜伏期 ,增多射精次数。
    RESULT Haima Zhuangyang Capsule can reduce the body weight of rats, increase their autonomous activities, prolong swimming time, markedly shorten the incubation period for the erection of penis of mice and increase the mating ability of normal male rats.
    结果用海马壮阳软胶囊可使大剂量氢化可的松造成的肾阳虚模型小鼠体重下降减少 ,自主活动增多 ,游泳时间延长 ,并能显著缩短小鼠阴茎勃起潜伏期 ; 使去势大鼠的包皮腺系数、前列腺 +精液囊系数、提肛肌系数提高 ,并能显著缩短大鼠阴茎勃起潜伏期 ;
    CONCLUSIONS The effect of Icariin on penile erection may be mediated by increasing cGMP levels in CC for enhancing the relaxation response of CC.
    结论 淫羊藿苷对阴茎勃起的作用机制与其能提高海绵体平滑肌cGMP浓度而增强阴茎海绵体平滑肌松弛作用有关
    Objective To find the relationship between the gene expression of NOS and the effects of Bushentongluo Formula (BF) on the erection of penis.
    目的 探讨一氧化氮合酶 (NOS)基因表达与补肾通络方在阴茎勃起中的关系。
    Conclusion BF can exert an important role in the erection of penis through regulating the expression of NOS mRNA.
    结论 补肾通络方可能通过调节NOSmRNA表达而在阴茎勃起中发挥重要作用。
 

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