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    Patients with extensive mediastinal lymph node metastasis, more node metastasis and non-squamous carcinoma showed significantly higher incidence of brain metastasis than those with limited mediastinal lymph node metastasis, fewer positive mediastinal lymph nodes and squamous carcinoma (P=0.000, P=0.000, P=0.013).
    多个区域纵隔淋巴结转移、多个纵隔淋巴结转移以及非鳞癌患者的脑转移发生率显著高于单区域纵隔淋巴结转移、纵隔淋巴结转移数目较少以及鳞癌患者(P=0.000,P=0.000,P=0.013)。
    Conclusion High risk factors of brain metastasis in LANSCLC patients after complete resection of the cancer include non-squamous carcinoma, extensive and more mediastinal lymph node metastasis.
    结论局部晚期NSCLC术后脑转移高危因素有:非鳞癌、纵隔多区域淋巴结转移、纵隔多个淋巴结转移。
    The percentage of adenocarcinoma and others in studygroup was 32.1%(17/36),but 8.6%(54/625)in control group(P<0.001).
    非鳞癌患者所占比例研究组为32.1%(17/36),对照组仅8.6%(54/625)(p<0.001)。
    In this study, the serum level of squamous cell carcinoma antigen(SCCAg) was measured using IMx system by micropartical enzyme immunoassay(MEIA) method in 105 subjects,including 25 healthy pereons(N1), 20 benign pulmonary disease(BPD), 26 patients with non-squamous cell carcinoma(non-SCC) of lung and 34 patients with squamous cell carcinoma(SCC) of lung.
    本实验采用全自动快速荧光酶分析系统(IMx),用微粒子酶免疫测定法(MEIA)测定了105人血清鳞状细胞癌抗原(SCCAg)水平,其中34例肺鳞癌(SCC),26例肺非鳞癌(NSCC)患者血清SCCAg水平,以20例肺良性疾病和25例健康人为对照组。
    Presumed N2disease was given to in all 16 cases of squamous carcinoma, however only 2 were true(11.1 % ). On the other hand 14 true N2 disease (56% ) presented in 25 cases of adenocarcinoma with presumed N2 disease (P<0.01).
    鳞癌患者普遍为假定的N2病变,但真正N病变发生率低(2/16例,11.1%),和非鳞癌患者(14/25例,56%)对比,差异有非常显著性(P<0.01)。
    The 1 and 2 year survival rates were as follows:squamous 80.3%,43.6%,nonsquamous 62.4%,32.1%( P =0.005);
    在各分组中,一、二年生存率为:鳞癌患者80.3%,43.6%,非鳞癌患者62.4%,32.1%(P=0.005);
    26% and 62% for squamous and non squamous cell carcinoma ( P <0 001);
    鳞癌为26%,非鳞癌为62%9(P<0.001);
    Results:① The positive rates of SCC antigen were significant different among SCC pre treament group and post treatment group,non SCC group,benign disease group, and control group (P0.05).
    结果 :鳞癌抗原在治疗前鳞癌患者血清中阳性率与正常对照组、治疗后组、非鳞癌组、良性疾病组有显著性差异( P0.05)。
    The frequency of loss of FHIT was significantly higher in squamous cell carcinomas (SqCCs)than that in non-SqCCs(72.7% vs 39.1%;χ2=6.32,P=0.012).
    肺鳞癌(SqCCs)中FHIT蛋白缺失率明显高于非鳞癌(non SqCCs)(72.7%vs39.1% ;χ2 =6.32,P=0.012) ;
    The number of the risk factors(blood g roup B and non-squamous )were neg atively related to prog nosis acc ording to multivariate analysis in s tag e Ⅲa NSCLC(the 5-year survival rates:43.5%vs 23.7%vs 4.0%,P<0.001).
    随着预后不良因素(非鳞癌和B型血)的增加,Ⅲa期患者5年生存率相应呈下降的趋势(43.5%vs23.7%vs4.0%,P<0.001)。
    Conclusion:Cervical cancer in young women has feature of bulky tumor and higher rate of nonsquamous carcinoma.
    结论 :年轻妇女宫颈癌除了有瘤体大、非鳞癌比例高的特点外 ,无其他预后不良的病理特征。
    There was a significant relationship in both abnormal expressions between non-squamous cell cancer (non-SqCC) and non-smokers, but not between SqCC and smokers.
    两者的异常表达在非鳞癌 (non -SqCC)和非吸烟的肺癌者中明显相关 ,而在肺鳞癌和吸烟者中无相关性。
    ,except that Fhit abnormal expression was found more in smokers (P= 0.032),and in squamous cell cancer(SqCC,P<0.001) whole P16 was seen more often in non-SqCC(P=0.025),and that P53 positive expression was significantly higher in N2 metastasis(P=0.039).
    除了Fhit异常表达显著多见于鳞癌 (SqCC ,P <0 .0 0 1)和吸烟者 (P =0 .0 32 )、P16多见于非鳞癌 (non SqCC)以及P5 3异常多见于N2淋巴结转移 (P =0 .0 39)外 ,三者的异常表达与其他临床病理参数 (包括年龄、性别、肿瘤大小和分期等 )均无相关性。
    Methods The expression of p63 and CK5/6 protein was identified by using Elivision's immunohistochemical essay in the paraffin embed tissue sections of 102 cases of squamous cell carcinomas and 98 cases of non-squamous cell carcinomas respectively.
    方法 采用免疫组织化学EliVision法检测10 2例鳞癌和98例非鳞癌组织p6 3和CK5 / 6蛋白表达。
 

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