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急性加重期
    Clinical study of integrated chinese traditional and western medicine for treating acute aggravation period of chronic cor pulmonale in 76 cases
    中西医结合治疗慢性肺原性心脏病急性加重期76例临床研究
    Objective It is to discuss the changes of soluble in tercellular adhesi on molecule-1 (sICAM-1), tumor necrosis factor-α(TNF-α) and interleukin-8 (IL- 8) in serum during acute aggravation period and stable period of chronic obstruc tive pulmonary disease (COPD), and to realize the net adjustive relation among t he three that in COPD attack.
    目的 探讨慢性阻塞性肺疾病 (COPD)急性加重期和稳定期血清中可溶性细胞间黏附分子 (sICAM - 1)、肿瘤坏死因子 (TNF -α)和白细胞介素 - 8(IL - 8)表达的变化 ,以了解三者在COPD发病中的网络调节关系。
    Methods The levels of sICAM-1, TNF-α and IL-8 in serum of 15 case s duri ng acute aggravation period and stable period of COPD were detected with ELISA.
    方法 采用酶联免疫吸附法 (ELISA)检测 15例COPD患者急性加重期、稳定期的sICAM - 1,TNF -α和IL - 8水平。
    Results The sICAM-1 level in acute aggravation period of COPD was obviously high er than that in stable period (P<0.05).
    结果 COPD患者急性加重期血清sICAM- 1水平明显高于稳定期 (P <0 .0 5 )。
    Clinic Therapeutic Effect of Mucosolvan Treat Acute Aggravation Period of Chronic Pulmonary Heart Disease
    沐舒坦佐治慢性肺源性心脏病急性加重期的临床疗效观察
    Objective:To observe the effect of integrated chinese traditional and western medicine for treating acute aggravation period of chronic cor pulmonale.
    目的 :观察中西医结合治疗慢性肺原性心脏病急性加重期的临床疗效。
    Methods:76 cases with acute aggravation period of chronic cor pulmonale were divided into treatment and control group,with 38 cases in each group. The patients in both groups were treated with the complex therapy of western medicine. On this basis of routine treatment,the patients in the treatment group were added chinese herbs.
    方法 :把慢性肺原性心脏病急性加重期患者76例 ,随机分为治疗组和对照组各38例 ,两组均按西医常规综合治疗 ,治疗组在常规治疗基础上加用中药 ,并对两组患者临床疗效、动脉血气、血液流变学指标进行对比分析。
    Conclusion:Integrated chinese traditional and western medicine for treating acute aggravation period of chronic cor pulmonale has obvious clinical effect,and is worth clinical application.
    结论 :中西医结合治疗慢性肺原性心脏病急性加重期具有显著临床疗效 ,值得在临床上推广应用
    Conclusion The sICAM-1 level in acute aggravation period of COPD h eightened refl ects the increase of the leucocyte adhesive function induced by sICAM-1 during t he disease course. That may be a new way to treat COPD.
    结论 COPD患者急性加重期血清sICAM - 1水平的增高 ,反映了疾病过程中sICAM - 1所介导的白细胞黏附活动增加 ,可作为一个新的治疗方向。
    Objective To evaluate the clinic effect of using Mucosolvan on the treatment of acute aggravation period of Chronic Pulmonary Heart Disease.
    目的探讨沐舒坦佐治慢性肺源性心脏病急性加重期的临床疗效。
    Conclusions Mucosolvan can improve the clinic effect of acute aggravation period of Chronic Pulmonary Heart Disease.
    结论沐舒坦能提高慢性肺源性心脏病急性加重期的疗效,改善预后。
 

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