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急性加重
    ELECTROCARDIOGRAM CHANGES IN THE PATIENTS WITE ACUTE EXACERBATION OF CHRONIC RESPIRATORY FAILURE
    慢性呼吸衰竭急性加重时的心电图变化
    ANTITHRQMBIN-Ⅲ: Ag AND FIBRONECTIN MEASUREMENT IN ACUTE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE IN ELDERLY PERSONS
    老年慢性阻塞性肺疾病急性加重期AT-Ⅲ:Ag和FN的相关研究
    Clinical Significance of C-reactive Protien and Haptoglobin in Acute Exacerbation of Chronic Obstructive Pulmonary Diseases in Elderly Patients
    老年COPD急性加重期C-反应蛋白和触珠蛋白的临床意义
    THE CHANGE AND CLINICAL SIGNIFICANCE OF BLOOD β_2-microglobulin In ACUTE EXACERBATION OF 55 SENILE PATIENTS WITH COR PULMONALE
    55例老年慢性肺心病急性加重期β_2微球蛋白测定的临床意义
    The Effects of Taking Different Kinds of Protein on Protein Synthesis during Acute Exacerbation in Patients with Cor Pulmonale
    摄入不同蛋白质对慢性肺心病急性加重期蛋白质合成的影响
    Objective To investigate clinical value of the serum level of interleukin-6(IL-6)、interleukin-8(IL-8) and tumor necrosis factorα(TNF-α) in patients with acute exacerbation of chronic obstructive pulmonary disease before and after 10-14 d therapy.
    目的探讨慢性阻塞性肺疾病(COPD)急性加重期治疗后外周血细胞因子IL-6、IL-8、TNF-α的临床意义。
    Methods The serum samples were collected and prepared from 32 inpatients with acute exacerbation of chronic obstructive pulmonary disease before and after 10-14 days therapy. IL-6,IL-8 and TNF-αin serum was detected by ELISA and blood routine and pulmonary function were detected in all patients.
    方法选择呼吸科32例COPD急性加重期住院患者,分别于治疗前及10-14 d治疗病情缓解后行血常规检查,肺功能检查,用ELISA法检测血清IL-6、IL-8、TNF-a浓度。
    Results The percentage of peripheral blood neutrophilic granulocyte and serum level of IL-6,IL-8 and TNF-α in patients with acute exacerbation of chronic obstructive pulmonary disease before treatment were significantly higher than that after therapy(P<0.01). The FEV_1 level of pulmonary function in patients with acute exacerbation of chronic obstructive pulmonary disease was notable lower than that after therapy(P<0.01).
    结果COPD急性加重期时外周血中性粒细胞占白细胞总数百分比(Neu/Leu%),血清IL-6、IL-8、TNF-a浓度均明显高于治疗后水平(P<0.01),而急性加重期FEV1明显低于治疗后水平(P<0.01)。
    Objective It is to comprehend the preponderance state of Th1/Th2 in peripheral blood of phlegm-heat and phlegm-dampness syndromes patients with chronic obstructive pulmonary disease(COPD) in acute exacerbation stage.
    目的了解慢性阻塞性肺病(COPD)急性加重期痰热型、痰湿型患者外周血中Th1/Th2细胞的优势状态。
    Conclusion Phlegm-heat syndrome patient with COPD in acute exacerbation stage shows the preponderance state of Th2 and phlegm-dampness syndrome shows the preponderance state tendency of Th1.
    结论痰热型COPD急性加重期表现为Th2优势状态,痰湿型表现为Th1优势状态趋势。
    The level of PaO2 had a negative relation with serum myocardial enzymes(r = -0.67~-0.87,P<0.01) in the COPD patients during acute exacerbation period.
    COPD急性加重期患者PaO2水平与对应的血清心肌酶呈直线负相关(r=-0.67~-0.87,P<0.01)。
    In pathogens of acute exacerbation of chronic obstructive pulmonary disease,gram negative bacteria occupied 73.9%,with Pseudomonas aeruginosa and Klebsiella pneumoniae as the most common pathogens(18.2% and 13.6%,respectively).
    慢性阻塞性肺疾病急性加重期患者感染的病原菌中革兰阴性杆菌占73.9%,铜绿假单胞菌和肺炎克雷伯菌最常见,分别为18.2%和13.6%;
    Objective To investigate the changes of interleukin(IL)-17 in plasma of patients with chronic obstructive pulmonary disease(COPD) both during acute exacerbation and stable stage with and its relationship with interleukin 8 and leukotriene B4(LTB4).
    目的观察慢性阻塞性肺疾病(COPD)急性加重期患者和急性加重期缓解患者的血浆白介素17(IL-17)、白介素8(IL-8)及白三烯B4(LTB4)含量变化。
    Results The concentrations of IL-17,IL-8 and LTB4 in patients with COPD during acute exacerbation were significantly higher than those in patients with COPD during stable stage and in the control subjects(P<0.05). The concentrations of IL-17,IL-8 and LTB4 in patients with COPD during stable stage were significantly higher than those in the control subjects(P<0.05).
    结果COPD急性加重期患者血浆IL-17、IL-8及LTB4水平明显高于急性加重期缓解患者和健康对照者,差异有统计学意义(P<0.05),COPD急性加重期缓解患者血浆IL-17、IL-8及LTB4水平亦明显高于健康对照者,差异有统计学意义(P<0.05)。
    The levels of IL-17 in patients with COPD both during acute exacerbation and stable stage correlated positively with those of IL-8 and LTB4.Conclusion The concentrations of IL-17,IL-8 and LTB4 in patients of COPD were significantly increased.
    COPD急性加重期患者和急性加重期缓解患者血浆IL-8、LTB4含量均与IL-17呈正相关。
    Acute exacerbation of chronic obstructive pulmonary disease(AECOPD) is related to the rapid decline of lung function.
    慢性阻塞性肺疾病急性加重(AECOPD)导致肺功能迅速下降。
    Objective To monitor drug resistance of Pseudomonas aeruginosa in patients with acute exacerbation of chronic obstructive pulmonary disease(AECOPD).
    目的监测慢性阻塞性肺疾病急性加重(acute exacerbation of chronic obstructive pulmonary disease,AECOPD)患者铜绿假单胞菌感染的耐药现状。
    Objective To evaluate clinic significance of interleukin-8 (IL-8) in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD), and to study the correlation between IL-8 and lung function.
    目的评价慢性阻塞性肺疾病(COPD)患者急性加重期血清白细胞介素8(IL-8)的变化特点及其与肺功能的相关性,探讨IL-8在COPD中的临床意义。
    Methods The serum level of IL-8 were measured in 63 patients with acute exacerbation of COPD before and after treatment. There were examinations in all patients on forced expiratory volume in one second of forced expiratory volume (FEV1/FVC), and their correlation with IL-8 and lung function.
    方法分别测定63例COPD急性加重期患者治疗前后血清IL-8水平及一秒钟用力呼气容积/用力肺活量(FEV1/FVC),并进行相关性分析。
    Results IL-8 concentration in serum of acute exacerbation of COPD after treatment was significantly higher than that before treatment (P <0.001).
    结果COPD急性加重期患者治疗前后IL-8水平对比分析具有显著差异(P<0.001)。
 

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