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急性发作期
    1,6-Fructose-diphosphate supplement in treating 76 patients with acute exacerbation of chronic pulmonary heart disease
    加用1,6-二磷酸果糖治疗慢性肺心病急性发作期76例
    Clinical Analysis of Secondary Fungus Infection in Patients with Chronic Obstructive Pulmonary Disease in Acute Exacerbation
    慢性阻塞性肺疾病急性发作期继发真菌感染的临床分析
    Results Sera from patients with acute exacerbation asthma had much higher levels of sCD86 (585.4 + 20.5 IU/ml) than sera from stable asthmatics (479.6 + 15.7 IU/ml, p < 0.001) and healthy individuals (435.1 + 13.8 IU/ml, p < 0.001), and there was no difference between the two latters (p = 0.079).
    结果 急性发作期哮喘患者血清sCD86(585.4±20.5kU/L)水平显著高于缓解期患者(479.6±15.7kU/L,P<0.001)和正常水平(435.1±13.8kU/L,P<0.001),而缓解期患者与正常对照组之间没有差别(P=0.079)。
    (2) During acute exacerbation imbalance of Tcl/Tc2 ratio shows the disorder of immune function,though no significantly difference of CD8+ T cells in the patients with COPD than control subjects.
    (2)在重度COPD急性发作期,尽管CD8~+T细胞与正常对照组比较无差别,但是存在Tc1/Tc2比例失衡,有免疫功能紊乱。
    25 pathogenic organisms were recovered in concentrations≥lO~5 colony forming units (cfu) per milliliter in 17 of 20patients with acute exacerbation status.
    20例慢支急性发作期病人中,17例病人共培养出定量值≥1×10~5cfu/ml的致病菌25株,这些细菌浓度平均为10~(5.66±0.52)cfu/ml显著高于临床缓解期10~(3.19±0.81)cfu/ml(p<0.01)。
    Thirty-one patients with cor pulmonale during acute exacerbation were randomly divided into the following two groups: treatment group(group A,17 cases)and control group(group B,14 cases).
    本文对31例慢性肺心病急性发作期患者,随机分为治疗组(A组)17例和对照组(B组)14例.
    ②The patients with acute exacerbation of asthma had higher percentages of CD 11a ,CD 11b and CD 44 compared with the controls ( P <0 01),but no difference from the relief asthmatic patients.
    ②哮喘急性发作期患儿 P B M Cs 表面 C D11a、 C D11b及 C D44粘附分子表达较正常人均明显增高( P 均< 0001),但与缓解期患儿相比无显著差异。
    \ Results\ The results indicated that the level of serum TNF α of patients with simple chronic bronchitis in acute exacerbation was higher significantly than that of the control group ( F=126.49, q=118.55, P < 0.01 ).
    3结果 慢性支气管炎急性发作期病人 TNF- α水平明显高于对照组 (F=12 6 .49,q=118.5 5 ,P<0 .0 1) ;
    The level of serum TNF α of those who met clinical control standard was lower than that of chronic bronchitis in acute exacerbation ( q=22.36,P <0.01).
    临床缓解期病人 TNF- α水平明显低于急性发作期病人 (q=2 2 .36 ,P<0 .0 1)。
    METHODS: Serum samples from 86 patients with acute exacerbation of COPD (Group A) and 32 patients with stable COPD (Group B) were tested for the specific IgG and IgM of respiratory syncytial virus (RSV), adenovirus (Adv), Coxsackievirus (Cox) and Cytomegalovirus (CMV) by Biochip technique-indirect immunofluorescence test.
    方法 :收集了COPD急性发作期患者 86例 (A组 )和COPD稳定期患者 32例 (B组 ) ,采用生物薄片技术对患者血清进行了呼吸道合胞病毒 (RSV)、腺病毒(Adv)、柯萨奇病毒 (Cox)和巨细胞病毒 (CMV)特异抗体IgG及IgM检测 .
    Results The concentrations of IL 17 both in patients with COPD during acute exacerbation and with asthma were significantly higher than that in the control subjects ( P <0.001).
    结果 与健康对照组比较 ,COPD急性加重期与哮喘急性发作期患者诱导痰中IL 17水平增高 (P <0 0 0 1)。
    Methods: Serum samples from 86 patients with acute exacerbation of COPD (Group A), 32 patients with stable COPD (Group B) were tested for the specific IgG and IgM for Respiratory Syncytial virus (RSV), Adenovirus (ADV), Coxsackievirus (COX) and Cytomegalovirus (CMV) with Biochip technique-indirect immunofluorescence test.
    方法收集了COPD急性发作期患者86例(A组)和COPD稳定期患者32例(B组),采用生物薄片技术对患者血清进行了呼吸道合胞病毒(RSV)、腺病毒(Adv)、柯萨奇病毒(Cox)、巨细胞病毒(CMV)特异性抗体IgG、IgM检测。
    Results The plasma levels of D-dimmer, VIIIR:Ag and VIII:C in patients with acute exacerbation of chronic pulmonary heart disease were significantly higher than that of control group (P<0.01).
    结果肺心病急性发作期血浆D-二聚体、VIII:Ag和VIII:C水平与正常人相比明显增高(P<0.01)。
    Results (1)Serum leptin, TNF-αand sTNFR1 levels were evidently higher in acute exacerbation than those in control group.
    结果:急性发作期COPD两组血瘦素、TNF-α和sTNFR1高于稳定期和正常组;
    Objective:To study the variation and significance of IL-8 and MMP-9 in patients with chronic obstructive pulmona- ry disease(COPD) during an acute exacerbation and at stable period.
    目的:探讨慢性阻塞性肺病(COPD)患者急性发作期和缓解期血清IL-8和MMP-9变化的临床意义。
    Methods:Enzyme-linked immunosorbent assay was used to messure the serum levels of IL-8 and MMP-9 in 20 normal person,23 patients with COPD during an acute exacerbation and at a stable period.
    方法:采用ELISA方法,分剐检测23例患者在COPD急性发作期、缓解期及20例正常人血清IL-8和MMP-9水平,并进行比较。
    Results:The serum level of IL-8 in patients with COPD during an acute exacerbation was significantly high- er than that of at stable period (P<0.01).
    结果:COPD急性发作期IL-8水平(197.27±65.44)pg·ml~(-1)明显高于缓解期(39.94±9.55)pg·ml~(-1)(P<0.01),两者间血清MMP-9水平则无显著差异(P>0.05)。
    Results During acute exacerbation,there was significant difference in FEV_1 and PAQLQ score before and after the ICS therapy in the therapy group(p<0.05)and the longer the inhalation therapy the greater the improvement was;
    结果急性发作期,治疗组的FEV1(1秒钟用力呼气量)和PAQLQ评分均值在治疗前后有显著性差异(p<0.05); 坚持治疗时间越长,改善越明显。
    During the course without acute exacerbation,there wasn't significant difference in FEV_1 and PAQLQ score before and after the ICS therapy between the two groups(p>0.05).
    非急性发作期,两组治疗前后的FEV1、PAQLQ评分均值无显著性差异(p>0.05)。
    Effect of Glucocorticoid Therapy Upon Glucose Metabolism in COPD Patients With Acute Exacerbation
    糖皮质激素治疗对COPD急性发作期患者糖代谢的影响
 

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