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    Measurement of granulysin mRNA expression in peripheral blood mononuclear cells of the acute hepatitis B patients and its clinical significance
    急性乙型肝炎患者外周血单个核细胞颗粒溶素mRNA定量测定及临床意义
    In the groups of acute hepatitis B patients and serious hepatitis B patients, S/CO ratio of HBsAg in the HBeAg positive patients were higher than that of the HBeAg negative patients ( P <0.05, P<0.01 ).
    在急性乙肝组和重症乙肝组中 ,乙肝e抗原 (HBeAg)阳性患者的HBsAgS/CO值显著高于HBeAg阴性患者 (P <0 .0 5 ) ,但在慢性乙肝、肝硬化和肝癌组中差异无显著性 (P >0 .0 5 )。
    Results The medians of percentages of HBV specific CD8+ cells of total CD8+ cells were 0.20%(0.02%~2.04%) in 11 acute hepatitis B patients and 0.05%(<0.01%~0.65%) in 16 chronic hepatitis B patients respectively. There was statistical difference between the two groups(P<0.01).
    结果  11例HLA A2 + 的急性乙肝患者外周血特异性CD8+ T细胞为 0 0 2 %~ 2 0 4 % ,中位数为 0 2 0 % ,16例HLA A2 + 的慢乙肝患者为<0 0 1%~ 0 6 5 % ,中位数为 0 0 5 % ,二组之间差有显著性 (P <0 0 1)。
    In three control groups including 15 HLA-A2+ normal people, 13 HLA-A2- acute hepatitis B patients and 19 HLA-A2-chronic hepatitis B patients, none of percentages of HBV specific CD8+ cells exceeded 0.02%.
    15例HLA A2 + 正常对照组、13例HLA A2 -急性乙肝对照组和 19例HLA A2 -慢性乙肝对照组的特异性的CD8+ T细胞均不超过0 0 2 %。
    In acute hepatitis B patients, PreS_2 becomes negative earlier than HBE-DNA, which suggests a good prognosis of disease.
    在急性乙型肝炎患者中,PreS_2先行HBV-DNA阴转,提示疾病的预后良好。
    Clinical Observation of Acute Hepatitis B Patients Treated with HBV-TF
    乙肝特异转移因子治疗急性乙型肝炎的临床观察
    Analysis of genotypes in acute hepatitis B patients.
    急性乙型肝炎患者乙型肝炎病毒基因分型及意义
    Observation of the progress and Effects of anti-virus therapy in acute hepatitis B patients
    急性乙型肝炎的临床转归及抗病毒效果观察
 

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