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慢性坐骨神经
    Effect of Intrathecal Ketamine Injection on the Expresstion of NMDA-2B Protein in the Spinal Cord on Rat Models by Chronic Constriction Injury
    氯胺酮鞘内注射对慢性坐骨神经损伤大鼠脊髓NMDA-2B蛋白表达的影响
    Methods On the chronic constriction injury (CCI) rats, 32 rats were randomly divided into four groups (n=8): NS group, Bac1 group, Bac2 group and Bac3 group.
    方法行为学实验,建立慢性坐骨神经结扎损伤模型,神经结扎后3d形成神经病理性痛的32只SD大鼠随机分为4组(n=8):NS组,Bac1组,Bac2组,Bac3组,鞘内分别注射生理盐水、0·1μg、0·3μg或1·0μg巴氯芬,注射容积均为10μL。
    Objective To compare the establishment and afficacy of three neuropathic pain models:chronic constriction injury of sciatic nerve(CCI), spinal nerve ligation (SNL) and spared nerve injury(SNI).
    目的比较慢性坐骨神经缩窄损伤(CCI)、脊神经结扎(SNL)、保留性神经损伤(SNI)三种神经病理性疼痛模型产生疼痛的效果。
    Aim To investigate the role of T type calcium channel of spinal cord and supraspinal on the pain threthold of the rats following chronic constriction injury(CCI) of the sciatic nerve.
    目的观察鞘内和侧脑室内注射T型钙通道阻断剂对慢性坐骨神经结扎大鼠痛阈的影响,探讨脊髓和脊髓上水平T型钙通道在神经病理性疼痛中的作用。
    Effect of intravenous ketamine on the ectopic discharges of the spinal dorsal horn in rats with chronic constriction injury
    氯胺酮对慢性坐骨神经损伤大鼠脊髓背角异位放电的影响
    MIBEFRADIL ADMINISTERED INTRATHECALLY INHIBITS MECHANICAL AND HEAT HYPERALGESIA FOLLOWING CHRONIC CONSTRICTION INJURY(CCI) OF THE SCIATIC NERVE IN RATS
    鞘内注射米贝地尔抑制慢性坐骨神经结扎大鼠机械痛敏和热痛敏
    Expression of glia fibrillary acidic protein and phosphorylated extracellular signal-regulated kinase in the hippocampus of chronic constriction injury rats
    慢性坐骨神经损伤大鼠海马GFAP和pERK表达的变化
    The effect of mibefradil administered intrathecally and lateral ventricle to the pain threshold of the rats following chronic constriction injury(CCI) of the sciatic nerve
    鞘内和侧脑室内注射米贝地尔对慢性坐骨神经松结扎大鼠痛阈的影响
    Effects of ketamine on apoptosis and expression of apoptosis-related protein of spinal dorsal horn neurons in rat model of chronic constriction injury to sciatic nerve
    氯胺酮对慢性坐骨神经压迫性损伤大鼠脊髓背角神经元凋亡及Bax和Bcl-2的表达影响
    Objective To evaluate the effects of intrathecal (i.t.) administration of ketamine on neuronal nitric synthase activity of the spinal dorsal horn in a rat model of chronic constriction injury (CCI).
    目的 探讨鞘内注射(i.t.)氯胺酮对慢性坐骨神经挤压损伤大鼠(CCI)脊髓背角一氧化氮合酶(NOS)活性的影响。
    Objective To explore the mechanisms of the hyperalgesia in the spinal cord and the effect of the morphine on the c-fos expression in spinal dorsal horn by investigating the changes of pain threshold elicited by touch-stimulus after the chronic constriction injury(CCI)of the sciatic nerve in rat.Methods Thirty female Sprague-Dawley rats were randomly divided into sham-operation group,CCI group and morphine group.
    目的 观察慢性坐骨神经收缩损伤 (CCI)大鼠触摸刺激后机械痛阈和热痛阈的变化 ,以研究吗啡 (2mg/kg)腹腔注射后对非伤害性刺激后脊髓后角c fos表达的影响 ,探讨脊髓痛觉调控机制。
    AIM:To evaluate the expression changes of glial fibrillary acidic protein(GFAP) and phosphorylated extracellular signal regulated kinase(pERK) in spinal cord of rats with chronic constriction injury(CCI) of sciatic nerve.
    目的:探讨慢性坐骨神经挤压损伤大鼠脊髓组织中胶质纤维酸性蛋白和磷酸化细胞外信号调节激酶表达的改变。
    Objective:To determine the expression of glia fibrillary acidic protein(GFAP) and phosphorylated extracellular signal-regulated kinase(pERK) in the hippocampus of chronic constriction injury(CCI) rats.
    目的:探讨慢性坐骨神经挤压损伤(CC I)大鼠海马组织中胶质原纤维酸性蛋白(GFAP)和磷酸化有丝分裂素激活蛋白激酶(pERK)表达的改变。
    Objective To investigate the effects of ketamine(Ket)on apoptosis and expression of apoptosis-related protein of spi- nal dorsal horn neurons in rat model of chronic constriction injury(CCI)to sciatic nerve.
    目的观察氯胺酮(Ket)对慢性坐骨神经压迫性损伤(CCI)大鼠脊髓背角神经元凋亡及凋亡相关蛋白Bax和Bcl-2表达的影响。
 

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