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    Simultaneously, the content of cyclic AMP in macrophage was markedly reduced, so the cyclic AMP/cyclic GMP ratio became decreased.
    同时,使巨噬细胞内的 cAMP含量明显降低,cGMP的含量也有升高趋向,导致 cAMP/cGMP比值显著减小。
    The rank order of the potencies of these agents on plasma cyclic GMP was atropine>scopolamine>B-7601.
    唯阿托品6.10mg/kg可提高cAMP/cGMP的比值(P<0.05)。 结果提示:三药对大鼠血浆cGMP含量的影响,阿托品>东莨菪碱>B-7601。
    The values of cyclic AMP and cycic GMP in fasting plasma and 24-hour urine of 31 patients with urinary stone and of 20 normal control subjects were determined by radioimmunoassay so as to calculate the values of filtered, clearance and nephrogenous cyclic AMP and cyclic GMP. It was found that all parameters of cyclic AMP are significantly elevated in stone patients group.
    本文采用放射免疫法测定了31例尿石症患者晨空腹血浆和24小时尿的cAMP和cGMP值,以此推算出滤过、清除和肾源性cAMP和cGMP值,并与20例健康人对照。
    The cyclic GMP - IR and cyclic AMP- IR in the epithelial cells of gastro- intestinal mucosaincreased gradually with the fetal age. The strongest reaction in the fetues occured in theirfifth or sixth months, and decreased gradually after the seventh month.
    采用SPA间接酶标免疫组化方法,显示胎儿的胃肠粘膜上皮细胞的cGmp—IR和cAmp—IR显色反应随胎龄月份增高逐渐加深,第七胎月后逐渐减弱接近成年人。
    The levels of cyclic AMP and cyclic GMP of seminal plasma were randomly deter-mined in accompany with routine examinations of semen in 52 cases.
    随机测定了52例精浆中环核苷酸(cAMP 和 cGMP)浓度。
    Cyclic AMP (cAMP) and cyclic GMP (cGMP) levels of peripheral blood lymphocytes (PBLS) of patients with acute leukaemia were estimated and compared with those of normal controls in vitro.
    利用放射免疫分析法研究了急性白血病患者外周血淋巴细胞内环核苷酸(cAMP、cGMP)含量的变化及免疫干扰素对淋巴细胞内cAMP、cGMP水平的影响。
    Plasma cyclic GMP concentrations before and after valve replacement were measured by radioimmunoassay in 45 patients with rheumatic valvular disease.
    应用放免法测定45例风湿性心脏瓣膜病患者换瓣术前后血浆 cGMP 的变化。
    There were also significant differences between various sperm motilities and the levels of cyclic AMP and cyclic GMP in semen(P<0.01), the sperm motility and the levels of cyclic AMP and cyclic GMP had a significant correlation (P<0.05), The results indicate that the level of cyclic AMP is connected with the density of spermatozoa.
    在不同精子活力的两组间其cAMP和cGMP含量均有显著性差异(P<0.01); 精子活力与cAMP和cGMP含量呈显著正相关(P<0.05)。
    It has been reported that morphine or opiate-like substances(OLS)can af-fect the contents of cyclic AMP and/or cyclic GMP in mammaian brain,but verylittle is know whether similar effects also occur in spinal cord.
    有资料表明,吗啡或脑啡肽可影响脑内 cAMP 与 cGMP 的含量,但对脊髓内 cAMP 与cGMP 的含量有何影响,未见报道。
    Using RIA method,we showed that morphine significantly decreased the content of cyclic AMP inthe rat spinal cord in vivo and in vitro and this effect could be completely blocked bynaloxone,while the concentration of cyclic GMP in rat spinal cord is unchanged.
    本实验采用放射免疫分析(RIA)方法研究的结果表明,吗啡可使大鼠离体与在体脊髓内 cAMP 的含量明显降低; 而对脊髓内 cGMP 的含量则无明显影响;
    To investigate the circadian change in the plasma atrial natriuretic peptide (ANP)concentrations and its relation to cyclic AMP(cAMP), cyclic GMP(cGMP) and serumsodium, blood samples from twenty-two normal subjects (16men and 6 women, mean age21.5 years) were collected and systolic blood pressure(SBP) and heart rate(HR) recor-dad every 8h over a 24h period.
    用放射免疫法测定22名(男16,女6)正常人安静卧位时血浆心钠素(ANP)、环磷腺苷(cAMP)、环磷鸟苷(cGMP)在24、8和16时的值,同时测定血清钠(Na)、收缩压(SBP)和心率(HR)值。
    Plasma cyclic nucleotides were measured for 55 outpatients with migraine. Plasma cyclic AMP and cyclic GMP were simultaneously observed in 44 outpatients with migraine.
    本文研究了55例偏头痛血浆环核苷酸含量变化,并对44例同步测了血浆CAMP、CGMP。
    Plasma atrial natriuretic factor(ANF) ,cyclic GMP (cGMP) ,cyclic AMP (cAMP)and angiotensin II (ATII) contents were measured with radioimmunoassay in 16 pilots before and after the complex aerobatic flight . Sixteen ground personnel were used for control. The results showed that the difference ofplasma ANF, cGMP,cAMP and ATII contents between pilots and ground personnel were insignificantbefore flying (P>0.05).
    用放射免疫法测定了16名飞行员复杂特技飞行前后的血浆心钠素(ANF)、环磷酸鸟苷(cGMP)、环磷酸腺苷(cAMP)以及血管紧张素II(ATII)含量,并以16名地勤人员作对照结果发现,飞行前空地勤人员血浆ANF、cGMP、cAMP及ATII含量均无明显差异(P>0.05).
    Contents of plasma atrial natriuretic factor (ANF),cyclic GMP (cGMP), cyclic AMP (cAMP) and angiotensin Ⅱ(AT Ⅱ) were measured by radioimmunoassay in 16 pilots before and after the complex aerobatic flight. Sixteen ground personnel were in control group.
    用放射免疫法测定了16名飞行员复杂持技飞行前后的血浆心钠素(ANF)、环磷酸鸟苷(cGMP)、环磷酸腺苷(cAMP)以及血管紧张素Ⅱ(ATⅡ)含量,并以16名地勤人员作对照.
    Plasma levels of atrial natriuretic factor (ANF), cyclic GMP (cGMP), cyclic AMP(cAMP) and angiotensin Ⅱ(AT Ⅱ) were measured with radioimmunoassay in 16 pilots before, immediately and 6 h after complex aerobatics. Sixteen ground personnel were used as control.
    用放射免疫法测定了16名飞行员复杂特拉飞行前后的血浆心钠素(ANF)、环磷酸鸟苷(CGMP)、环磷酸腺音(cAMP)以及血管紧张素Ⅱ(ATⅡ)含量,并以16名地勤人员作对照。
    As an important intracellular se-cond messenger,cyclic GMP regulates variousfunctions of cells,such as visual and olfactorysignal transduction, vascular smooth musclerelaxation,lymphocyte activation and chemo-taxis of reproductive cell. In different kinds ofcells,cyclic GMP interacts with cGMp-depen-dent protein kinases,cGMp-regulated ionchannels,cGMp-regulated cyclic nucleotidephosphodiesterases or ADP-ribosyl cyclase re-spectively. This means that cyclic GMP canregulate cell functions through protein phos-phorylation or through pathways not directlyrelated to protein phosphorylation.
    cGMP作为胞内第二信使,主要通过cGMP依赖的蛋白激酶(cGPK),cGMP门控的离子通道,cGMP调节的环核苷酸磷酸二酯酶以及ADP核糖环化酶等后续途径,参与许多细胞功能的调控.cGMP既可以通过蛋白磷酸化,也通过与蛋白磷酸化不直接相关的信号传递途径来调控各类细胞的特定生理功能.
    To investigate'the influence of methylene blue (MB) on blood pressure of experimental endotoxic shock, we noticed that MB infusion can elevated mean arterial pressure (P<0. 01), decrease plasma cyclic GMP (P<0. 05), but did not change the atrial natriureti.
    为了观察美蓝对内毒素性休克血压的影响,作者通过动物实验后发现,对照组大白兔静注生理盐水前后,平均动脉压、血浆环磷酸鸟着、心钠素均无差异(P>0.05);
    Levels of cyclic AMP and cyclic GMP in synchronized cells , and activities of the two key enzymes (AC and PDE) responsible for the cyclic AMP metabolism were measured by applying the isotopic techniques.
    应用同位素标记技术,测定了同步细胞群体中cAMP和cGMP的水平、cAMP代谢途径中两个关键酶——腺苷酸环化酶(AC)和磷酸二酯酶(PDE)的活性节律。
    Interference experiments with the enzyme activator and inhibitor such as forskolin, 8-Br-cGMP and LY 83583, and analysis of the cell division cycle (CDC) and coupling messengers suggested that the peak pulse of cyclic AMP, circadian oscillation of the AC-cAMP-PDE system and phase-dependent regulation by cyclic GMP might be important coupling factors in downstream mediation between the circadian clock and the CDC.
    对细胞分裂节律和介导信使节律间的偶联分析,以及用forskolin、8-Br-cGMP和LY-83583等酶的激动剂和抑制剂所做的干涉实验结果表明,cAMP的峰值信号、AC-cAMP-PDE系统的昼夜振荡和cGMP的位相性调节是构成昼夜钟起博器和细胞节律之间下行性介导的重要中间环节。
    Conclusions These results suggest that NO in the forebrain produces a facilitation of the pain behavior of the rat and this facilitation is,at least,partially mediated via the NO-cyclic GMP pathway.
    结论NO在大鼠前脑对痛行为反应具有易化作用; 且部分是通过NO—cGMP通路实现的。
 

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