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血液肿瘤
    Alterations in the serum levels of TNF and TGF-α in patients with hematological malignancy and their clinical significance
    血液肿瘤患者血清TNF、TGF-α的水平及临床意义
    A clinical study of dental extraction in pediatric patients with hematological malignancy
    血液肿瘤患儿拔牙安全性的临床研究
    Clinical Study of Induction high dose therapy followed by Main- tenance with EPO in Anemic Hematological Malignancy Patients
    红细胞生成素大剂量冲击维持疗法治疗血液肿瘤贫血的临床研究
    This study is to determine whether induction high dose EPO followed by weekly maintenance usage could improve hemoglobin (Hb) levels in anemic hematological malignancy patients receiving chemotherapy. Methods The open-label, nonrandomized clinical study evaluated the response rate of induction EPO 120,000 U (40,000 U SC d1、d3、d5) followed by maintenance dose of 40,000 U SC once weekly for 3 weeks (d8、d15、d22).
    方法采用开放性非随机的临床研究方法,恶性血液肿瘤患者在化疗同时,于第1周采用EPO120,000U冲击用药(40,000U皮下d1、d3、d5),随后EPO每周40,000U皮下(d8、d15、d22)维持用药,共4周。
    Significance of the Changes of Plasma vWF,D-dimer and Antithrombin Levels in Patients with Hematological Malignancy
    血液肿瘤患者中血管性血友病因子、D二聚体、抗凝血酶检测的意义
    ObjectiveTo study alterations in the serum levels and the clinical significance of TNF and TGF-α in patients with hematological malignancy.
    目的 探究TNF和TGF α在血液肿瘤性疾病中的变化和病情及预后的关系。
    MethodsSerum levels of TNF and TGF-α were measured by immunoassay in 30 normal persons as controls and in 63 pateints with hematological malignancy before and after treatment and during deteriorating period of the disease.
    方法 用放射免疫分析法检测了血液肿瘤性疾病患者 (63例 )和正常健康人 (3 0例 )血清TNF和TGF α水平 ,对治疗前后、病情变化进行了比较。
    ResultsThe serum levels of TNF in patietns with hematological malignancy before treatment were much higher than those in normal controls (P<0.01). Of the same group patients the serum levels of TNF after treatment were much lower than those before treatment (P<0.01).
    结果 血液肿瘤性疾病患者治疗前TNF水平都明显高于正常组 (P <0 .0 1) ,治疗缓解后比治疗前明显降低 (P <0 .0 1)。
    Methods Heart function's clinical evaluation was performed during the pre-therapy and post-therapy in 136 elderly patients(≥60y)with hematological malignancy who were hospitalized in our department this year.
    方法对我科近年来收治的老年血液肿瘤患者(≥60岁)136例进行化疗前后心脏功能指标的临床分析。
    Results From Oct. 2003 to Dec. 2005, 42 cancer- related anemic hematological malignancy patients receiving concurrent chemotherapy were accrued.
    结果2003年10月~2005年12月共入组42例同期化疗的血液肿瘤贫血患者。
    Conclusion The determination of levels of vWF and D-D may be important for the evaluation of the effect of treatment in hematological malignancy. The decrease of AT activity probably reflect a bad prognosis and the severity of dis- ease.
    结论血液肿瘤患者存在不同程度的高凝状态,血浆vWF、D-D含量变化对病情和预后的评估有一定的参考价值,血浆AT水平降低是反映病情危重的指标。
 

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