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小叶性肝炎
    OKM1+ cells were only scattered in portal and intralobular areas in acute and chronic lobular hepatitis, but greatly increased in chronic hepatitis and associated with the activity degree in the liver and predominantly distributed at the edge of periportal and bridging necrosis areas.
    结果表明,急性肝炎和慢性小叶性肝炎的OKM_1~+细胞仅散在于门管区和小叶内,其占单个核细胞(MNC)的平均百分率低于8%。 慢性活动性肝炎的OKM_1~+细胞则明显增多,且主要分布于门管周围区和桥接坏死区的边缘,并与肝内病变的程度密切相关。
    Among fifteen patients who underwent liver biopsy, interface hepatitis and lobular hepatitis were observed in 11(73.3%) and 5(33.3%) patients, respectively. Rosetting of liver cells and liver fibrosis or cirrhosis were also detected in 3(20%) and 6(40%) patients respectively.
    在有肝穿刺活检组织资料的 15例患者中 ,11例 (73.3% )出现界板性肝炎 ,小叶性肝炎 5例 (33.3% ) ,玫瑰花结样改变 3例 (2 0 .0 % ) ,肝纤维化或肝硬化 6例 (40 .0 % )。
    The histological changes of liver tissues in theselesions of liver cell damage of mild degree 34 cases (80.5%) with interstitial inflammationchronic persistent hepatitis 18 (42.9%), lobular hepatitis 8 (19.3%), focal hepatitis8 (19.3%). nonspecific change 6 cases (14.3%), almost normal 2 cases (4.8%).
    其中CPH18例(42.9%),小叶性肝炎8例(19.38%),灶性肝炎8例(19.38%),非特异性改变6例(14.38%),基本正常2例(4.76%)。
    This paper was reported on the basis of 250 liver puncture biopsy specimens fromclinically diagnosed chronic persistent hepatitis (CPH). Among the patients 40 cases(16% of CPH) could be diagnosed as chronic lobular hepatitis (CLH).
    本文取自250例慢迁肝的肝穿刺组织,结合临床及免疫学检查,按组织学改变可明确诊断慢性小叶性肝炎(CLH)者40例,占慢迁肝的16.0%。
    It was found that chronic active hepatitis (CAH) group had a significant higher prevalence (80.7%),as compared with cirrhosis,chronic lobular hepatitis (CLH),acute hepatitis and hepatocellular carcinoma (HCC) groups.
    HBV DNA在慢性活动性肝炎中检出率最高(80.7%),显著高于肝硬化、慢性小叶性肝炎、急性肝炎及原发性肝癌组。
    Twenty-six patients underwent liver biopsy. The main histologic change was interface hepatitis (65%),lobular hepatitis,rosette of liver cells and bridging necrosis were observed in heavy cases.
    26例患者进行了病理组织学检查,肝组织病理变化以界面性肝炎为主(占65%),在重度患者则出现小叶性肝炎、玫瑰花结样改变、桥接样坏死等。
 

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